Pehlivantürk Kızılkan Melis, Kanbur Nuray, Akgül Sinem, Alikaşifoğlu Ayfer
Hacettepe University Faculty of Medicine, İhsan Doğramacı Children's Hospital, Clinic of Pediatrics, Division of Adolescent Medicine, Ankara, Turkey, E-mail:
J Clin Res Pediatr Endocrinol. 2016 Mar 5;8(1):92-5. doi: 10.4274/jcrpe.2297. Epub 2015 Dec 18.
Low triiodothyronine syndrome is a physiological adaptation encountered in anorexia nervosa (AN) and generally improves with sufficient weight gain. However, when a primary thyroid pathology accompanies AN, both the evaluation of thyroid hormone levels and the management of the co-morbid disease become more challenging. Hashimoto thyroiditis could complicate the management of AN by causing hyper- or hypothyroidism. AN could also negatively affect the treatment of Hashimoto thyroiditis by altering body weight and metabolic rate, as well as by causing drug non-compliance. We present the case of a 15-year-old boy with comorbid AN restrictive sub-type and Hashimoto thyroiditis. In this case report, we aimed to draw attention to the challenges that could be encountered in the diagnosis, treatment, and follow-up of patients with AN when accompanied by Hashimoto thyroiditis.
低三碘甲状腺原氨酸综合征是神经性厌食症（AN）中出现的一种生理适应性变化，通常随着体重的充分增加而改善。然而，当原发性甲状腺疾病与AN并存时，甲状腺激素水平的评估以及合并疾病的管理都变得更具挑战性。桥本甲状腺炎可通过导致甲状腺功能亢进或减退而使AN的管理复杂化。AN也可能通过改变体重和代谢率以及导致药物治疗依从性差而对桥本甲状腺炎的治疗产生负面影响。我们报告一例15岁男性患者，患有共病的AN限制型亚型和桥本甲状腺炎。在本病例报告中，我们旨在提醒人们注意AN合并桥本甲状腺炎患者在诊断、治疗和随访中可能遇到的挑战。
