Ballesteros-Gómez Ana, Jonkers Tim, Covaci Adrian, de Boer Jacob
Institute for Environmental Studies, VU University Amsterdam, De Boelelaan 1087, 1081 HV, Amsterdam, The Netherlands.
Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Wilrijk, Belgium.
Anal Bioanal Chem. 2016 Apr;408(11):2945-53. doi: 10.1007/s00216-015-9238-5. Epub 2016 Jan 12.
Plastics are complex mixtures consisting of a polymer and additives with different physico-chemical properties. We developed a broad screening method to elucidate the nature of compounds present in plastics used in electrical/electronic equipment commonly found at homes (e.g., electrical adaptors, computer casings, heaters). The analysis was done by (a) solvent extraction followed by liquid chromatography coupled to high accuracy/resolution time-of-flight mass spectrometry (TOFMS) with different ionization sources or (b) direct analysis of the solid by ambient mass spectrometry high accuracy/resolution TOFMS. The different ionization methods showed different selectivity and sensitivity for the different compound classes and were complementary. A variety of antioxidants, phthalates, UV filters, and flame retardants were found in most samples. Furthermore, some recently reported impurities or degradation products derived from flame retardants were identified, such as hydroxylated triphenyl phosphate and tetrabromobisphenol A monoglycidyl ether.
塑料是由聚合物和具有不同物理化学性质的添加剂组成的复杂混合物。我们开发了一种广泛的筛选方法，以阐明常见于家庭中的电气/电子设备（如电源适配器、电脑机箱、加热器）所使用的塑料中存在的化合物的性质。分析通过以下方式进行：(a) 溶剂萃取，然后将液相色谱与具有不同电离源的高精度/分辨率飞行时间质谱 (TOFMS) 联用，或 (b) 通过常压质谱高精度/分辨率TOFMS对固体进行直接分析。不同的电离方法对不同的化合物类别显示出不同的选择性和灵敏度，且具有互补性。在大多数样品中发现了多种抗氧化剂、邻苯二甲酸盐、紫外线吸收剂和阻燃剂。此外，还鉴定出了一些最近报道的源自阻燃剂的杂质或降解产物，如羟基化磷酸三苯酯和四溴双酚A单缩水甘油醚。
