Farhadpour F, Telmadarraiy Z, Chinikar S, Akbarzadeh K, Moemenbellah-Fard M D, Faghihi F, Fakoorziba M R, Jalali T, Mostafavi E, Shahhosseini N, Mohammadian M
Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
National Reference Laboratory for Arboviruses and Viral Hemorrhagic Fevers, Pasture Institute of Iran, Tehran, Iran.
Trop Med Int Health. 2016 Mar;21(3):340-7. doi: 10.1111/tmi.12667. Epub 2016 Feb 11.
Crimean-Congo haemorrhagic fever (CCHF) is a viral zoonotic disease with potentially fatal systemic effects on man. We aimed to determine the presence of CCHF virus among collected ticks from domestic livestock from October 2012 to September 2013.
A total of 1245 hard and soft ticks were collected from naturally infested ruminants in Marvdasht County, Fars Province, south of Iran. Nine tick species and one unidentified species in four disparate genera were detected. A total of 200 ticks were randomly selected and analysed by reverse transcription-polymerase chain reaction (RT-PCR) for the presence of CCHF virus genome.
The viral genome was detected in 4.5% (9 samples) of the studied tick population. The infected ticks belonged to the species of Hyalomma marginatum' Hyalomma anatolicum and Rhipicephalus sanguineus. The viruses detected in these three tick species were clustered in the same lineage as Matin and SR3 strains in Pakistan and some other Iranian strains. These results indicate that the ticks were wildly infected with a genetically closely related CCHF virus in the region.
Regular controls and monitoring of livestock to reduce the dispersion of ticks and providing information to those involved in high-risk occupations are urgently required.
克里米亚-刚果出血热（CCHF）是一种病毒性人畜共患病，可对人类产生潜在致命的全身影响。我们旨在确定2012年10月至2013年9月从家养牲畜采集的蜱中是否存在CCHF病毒。
从伊朗南部法尔斯省马尔夫达什特县自然感染的反刍动物身上共采集了1245只硬蜱和软蜱。检测到四个不同属中的九种蜱和一种未鉴定的蜱。随机选择200只蜱，通过逆转录-聚合酶链反应（RT-PCR）分析是否存在CCHF病毒基因组。
在所研究的蜱种群中，4.5%（9个样本）检测到病毒基因组。受感染的蜱属于边缘璃眼蜱、安纳托利亚璃眼蜱和血红扇头蜱。在这三种蜱中检测到的病毒与巴基斯坦的马丁和SR3菌株以及其他一些伊朗菌株属于同一谱系。这些结果表明，该地区的蜱被基因密切相关的CCHF病毒广泛感染。
迫切需要对牲畜进行定期控制和监测，以减少蜱的传播，并向从事高风险职业的人员提供信息。
