Mandewale Mustapha C, Thorat Bapu, Shelke Dnyaneshwar, Yamgar Ramesh
P.G. and Research Centre, Department of Chemistry, Government of Maharashtra, Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060, India.
Department of Chemistry, Chikitsak Samuha's Patkar-Varde College of Arts, Science and Commerce, Goregaon (West), Mumbai 400 062, India.
Bioinorg Chem Appl. 2015;2015:153015. doi: 10.1155/2015/153015. Epub 2015 Nov 25.
A new series of quinoline hydrazone derivatives and their metal complexes have been synthesized and their biological properties have been evaluated against Mycobacterium tuberculosis (H37 RV strain). Most of the newly synthesized compounds displayed 100% inhibitory activity at a concentration of 6.25-25 μg/mL, against Mycobacterium tuberculosis. Fluorescence properties of all the synthesized compounds have been studied.
已经合成了一系列新的喹啉腙衍生物及其金属配合物，并评估了它们对结核分枝杆菌（H37 RV菌株）的生物学特性。大多数新合成的化合物在浓度为6.25 - 25μg/mL时对结核分枝杆菌表现出100%的抑制活性。已经研究了所有合成化合物的荧光特性。
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