Maness David L, Khan Muneeza
University of Tennessee Health Science Center, Memphis, TN, USA.
Am Fam Physician. 2015 Dec 15;92(12):1058-64.
Insomnia affects 10% to 30% of the population with a total cost of $92.5 to $107.5 billion annually. Short-term, chronic, and other types of insomnia are the three major categories according to the International Classification of Sleep Disorders, 3rd ed. The criteria for diagnosis are difficulty falling asleep, difficulty staying asleep, or early awakening despite the opportunity for sleep; symptoms must be associated with impaired daytime functioning and occur at least three times per week for at least one month. Factors associated with the onset of insomnia include a personal or family history of insomnia, easy arousability, poor self-reported health, and chronic pain. Insomnia is more common in women, especially following menopause and during late pregnancy, and in older adults. A comprehensive sleep history can confirm the diagnosis. Psychiatric and medical problems, medication use, and substance abuse should be ruled out as contributing factors. Treatment of comorbid conditions alone may not resolve insomnia. Patients with movement disorders (e.g., restless legs syndrome, periodic limb movement disorder), circadian rhythm disorders, or breathing disorders (e.g., obstructive sleep apnea) must be identified and treated appropriately. Chronic insomnia is associated with cognitive difficulties, anxiety and depression, poor work performance, decreased quality of life, and increased risk of cardiovascular disease and all-cause mortality. Insomnia can be treated with nonpharmacologic and pharmacologic therapies. Nonpharmacologic therapies include sleep hygiene, cognitive behavior therapy, relaxation therapy, multicomponent therapy, and paradoxical intention. Referral to a sleep specialist may be considered for refractory cases.
失眠影响着10%至30%的人口,每年造成的总成本达925亿至1075亿美元。根据《国际睡眠障碍分类》第3版,短期失眠、慢性失眠和其他类型的失眠是三大主要类别。诊断标准为入睡困难、睡眠维持困难或尽管有睡眠机会仍早醒;症状必须与日间功能受损相关,且每周至少出现三次,持续至少一个月。与失眠发作相关的因素包括个人或家族失眠史、易唤醒、自我报告的健康状况不佳以及慢性疼痛。失眠在女性中更为常见,尤其是在绝经后和妊娠晚期,以及老年人中。全面的睡眠史可确诊。应排除精神和医学问题、药物使用及物质滥用作为促成因素。仅治疗合并症可能无法解决失眠问题。患有运动障碍(如不宁腿综合征、周期性肢体运动障碍)、昼夜节律障碍或呼吸障碍(如阻塞性睡眠呼吸暂停)的患者必须被识别并得到适当治疗。慢性失眠与认知困难、焦虑和抑郁、工作表现不佳、生活质量下降以及心血管疾病风险和全因死亡率增加有关。失眠可通过非药物和药物疗法进行治疗。非药物疗法包括睡眠卫生、认知行为疗法、放松疗法、多成分疗法和矛盾意向疗法。难治性病例可考虑转诊至睡眠专家处。