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成人扁桃体切除术的长期结果

Long-Term Results From Tonsillectomy in Adults.

作者信息

Senska Götz, Atay Halil, Pütter Carolin, Dost Philipp

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Marienhospital Gelsenkirchen GmbH, Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen.

出版信息

Dtsch Arztebl Int. 2015 Dec 11;112(50):849-55. doi: 10.3238/arztebl.2015.0849.

DOI:10.3238/arztebl.2015.0849
PMID:26763379
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4732178/
Abstract

BACKGROUND

Tonsillectomy is performed more than 400 000 times in the European Union each year, making it one of the most common operations. Nonetheless, there have been only a few long-term studies of quality of life after tonsillectomy.

METHODS

In 2004, data on the quality of life after tonsillectomy were obtained from adult German-speaking tonsillectomy patients by means of the Glasgow Benefit Inventory and a questionnaire specifically designed for that study. The present study concerns the further followup of these patients, sometimes many years later. 114 patients with recurrent tonsillitis were included in this descriptive study.

RESULTS

Of the 114 patients, 97 (85%) provided further data at 14 months, and 71 (62%) at ca. 7 years. The Glasgow Benefit Inventory revealed postoperative improvement of quality of life at 14 months and at 7 years, with median values of 16.67 points (quartile 11.11/25) and 13.89 points (quartile 8.33/25) (p=0.168). The mean number of annual episodes of sore throat fell from 10 preoperatively to 2 postoperatively (p=0.0001). The number of visits to the doctor, the intake of analgesic drugs and antibiotics, and the number of medical absences from work also declined significantly over the period of observation.

CONCLUSION

Tonsillectomy was associated with a longlasting improvement of health and quality of life, and with lower utilization of medical resources. The 62% response rate at 7 years leaves the question open whether patients with a favorable postoperative course may have been more likely than others to participate in the study.

摘要

背景

在欧盟,每年扁桃体切除术的实施次数超过40万次,使其成为最常见的手术之一。然而,关于扁桃体切除术后生活质量的长期研究却很少。

方法

2004年,通过格拉斯哥获益量表以及专门为该研究设计的问卷,收集了成年德语区扁桃体切除患者术后生活质量的数据。本研究关注这些患者多年后的进一步随访情况。这项描述性研究纳入了114例复发性扁桃体炎患者。

结果

114例患者中,97例(85%)在14个月时提供了进一步的数据,71例(62%)在约7年时提供了数据。格拉斯哥获益量表显示,术后14个月和7年时生活质量均有改善,中位数分别为16.67分(四分位数间距11.11/25)和13.89分(四分位数间距8.33/25)(p = 0.168)。每年咽痛发作的平均次数从术前的10次降至术后的2次(p = 0.0001)。在观察期内,看医生的次数、镇痛药和抗生素的使用量以及因病缺勤的天数也显著减少。

结论

扁桃体切除术与健康状况和生活质量的长期改善以及医疗资源利用率的降低相关。7年时62%的应答率使得术后恢复良好的患者是否比其他患者更有可能参与研究这一问题仍未明确。

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本文引用的文献

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A nationwide population-based cohort study on tonsillectomy and subsequent cancer incidence.一项基于全国人口的扁桃体切除术与后续癌症发病率的队列研究。
Laryngoscope. 2015 Jan;125(1):134-9. doi: 10.1002/lary.24864. Epub 2014 Aug 5.
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Predictive factors for quality of life after tonsillectomy among adults with recurrent pharyngitis: a prospective cohort study.复发性咽炎成人患者扁桃体切除术后生活质量的预测因素:一项前瞻性队列研究
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Acta Otolaryngol. 2013 May;133(5):499-503. doi: 10.3109/00016489.2012.728716.
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Improved quality of life in adults undergoing tonsillectomy for recurrent tonsillitis. Is adult tonsillectomy really a low priority treatment?成人因复发性扁桃体炎行扁桃体切除术的生活质量改善。成人扁桃体切除术真的是低优先级治疗吗?
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Dtsch Arztebl Int. 2010 Sep;107(36):622-8. doi: 10.3238/arztebl.2010.0622. Epub 2010 Sep 10.