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胰腺创伤的管理:一位胰腺外科医生的观点。

Management of pancreatic trauma: A pancreatic surgeon's point of view.

作者信息

Iacono Calogero, Zicari Marianna, Conci Simone, Valdegamberi Alessandro, De Angelis Michela, Pedrazzani Corrado, Ruzzenente Andrea, Guglielmi Alfredo

机构信息

Department of Surgery, Division of General Surgery, Unit of Hepato-Pancreato-Biliary Surgery, University of Verona Medical School, Verona, Italy.

Department of Radiology, University of Verona Medical School, Verona, Italy.

出版信息

Pancreatology. 2016 May-Jun;16(3):302-8. doi: 10.1016/j.pan.2015.12.004. Epub 2015 Dec 22.

Abstract

BACKGROUND

Pancreatic trauma occurs in 0.2% of patients with blunt trauma and 1-12% of patients with penetrating trauma. Traumatic pancreatic injuries are characterised by high morbidity and mortality, which further increase with delayed diagnoses. The diagnosis of pancreatic trauma is challenging. Signs and symptoms can be non-specific or even absent.

METHODS

A critical review of studies reporting the management and outcomes of pancreatic trauma was performed.

RESULTS

The management of pancreatic trauma depends on the haemodynamic stability of the patient, the degree and location of parenchymal injury, the integrity of the main pancreatic duct, and the associated injuries to other organs. Nevertheless, the involvement of the main pancreatic duct is the most important predictive factor of the outcome. The majority of pancreatic traumas are managed by medical treatment (parenteral nutrition, antibiotic therapy and somatostatin analogues), haemostasis, debridement of devitalised tissue and closed external drainage. If a proximal duct injury is diagnosed, endoscopic transpapillary stent insertion can be a viable option, while surgical resection by pancreaticoduodenectomy is restricted to an extremely small number of selected cases. Injuries of the distal parenchyma or distal duct may be managed with distal pancreatectomy with spleen preservation. At the pancreatic neck, when pancreatic transection occurs without damage to the parenchyma, a parenchyma-sparing procedure is feasible.

CONCLUSION

The management of pancreatic injuries is complex and often requires a multidisciplinary approach. Here, we propose a management algorithm that is based on parenchymal damage and the site of duct injury.

摘要

背景

胰腺创伤在钝性创伤患者中发生率为0.2%,在穿透性创伤患者中发生率为1%-12%。创伤性胰腺损伤的特点是发病率和死亡率高,延误诊断会进一步增加。胰腺创伤的诊断具有挑战性。体征和症状可能不具特异性,甚至不存在。

方法

对报告胰腺创伤管理及结果的研究进行了批判性综述。

结果

胰腺创伤的管理取决于患者的血流动力学稳定性、实质损伤的程度和部位、主胰管的完整性以及其他器官的相关损伤。然而,主胰管受累是预后最重要的预测因素。大多数胰腺创伤通过内科治疗(肠外营养、抗生素治疗和生长抑素类似物)、止血、清除失活组织和闭式外引流进行处理。如果诊断为近端导管损伤,内镜下经乳头置入支架可能是一种可行的选择,而胰十二指肠切除术仅限于极少数特定病例。远端实质或远端导管损伤可通过保留脾脏的远端胰腺切除术进行处理。在胰腺颈部,当胰腺横断而实质未受损时,保留实质的手术是可行的。

结论

胰腺损伤的管理很复杂,通常需要多学科方法。在此,我们提出一种基于实质损伤和导管损伤部位的管理算法。

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