• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

创伤后重症急性胰腺炎并发腹腔内感染：一例报告

Severe acute pancreatitis complicated with intra-abdominal infection secondary to trauma: A case report.

作者信息

Zhang Yu, Cui Yun-Feng

机构信息

Department of Surgery, Tianjin Nankai Hospital, Tianjin Medical University, Tianjin 300070, China.

Department of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Tianjin Nankai Hospital, Nankai Clinical School of Medicine, Tianjin Medical University, Tianjin 300100, China.

出版信息

World J Clin Cases. 2024 Sep 6;12(25):5821-5831. doi: 10.12998/wjcc.v12.i25.5821.

DOI:10.12998/wjcc.v12.i25.5821
PMID:39247729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11263061/
Abstract

BACKGROUND

Pancreatic trauma (PT) is rare among traumatic injuries and has a low incidence, but it can still lead to severe infectious complications, resulting in a high mortality rate. Acute pancreatitis (AP) is a common complication after PT, and when combined with organ dysfunction and sepsis, it will result in a poorer prognosis.

CASE SUMMARY

We report a 25-year-old patient with multiple organ injuries, including the pancreas, due to abdominal trauma, who developed necrotising pancreatitis secondary to emergency caesarean section, combined with intra-abdominal infection (IAI). The patient underwent performed percutaneous drainage, pancreatic necrotic tissue debridement, and abdominal infection foci debridement on the patient.

CONCLUSION

We report a case of severe AP and IAI secondary to trauma. This patient was managed by a combination of conservative treatment such as antibiotic therapy and fluid support with surgery, and a better outcome was obtained.

摘要

背景

胰腺创伤（PT）在创伤性损伤中较为罕见，发病率较低，但仍可导致严重的感染并发症，死亡率较高。急性胰腺炎（AP）是PT后的常见并发症，若合并器官功能障碍和脓毒症，预后将更差。

病例摘要

我们报告一名25岁因腹部创伤导致包括胰腺在内的多器官损伤的患者，该患者因急诊剖宫产继发坏死性胰腺炎，并合并腹腔内感染（IAI）。对该患者进行了经皮引流、胰腺坏死组织清创及腹腔感染灶清创。

结论

我们报告了一例创伤后严重AP和IAI的病例。该患者通过抗生素治疗和液体支持等保守治疗与手术相结合的方式进行处理，取得了较好的疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/e8feee2198f9/WJCC-12-5821-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/103c9fae6524/WJCC-12-5821-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/4b8f036c10ef/WJCC-12-5821-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/e0ad6d779feb/WJCC-12-5821-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/007acd2c86d1/WJCC-12-5821-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/e0fb244a597b/WJCC-12-5821-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/6580118509b4/WJCC-12-5821-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/6cc383de58ab/WJCC-12-5821-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/e8feee2198f9/WJCC-12-5821-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/103c9fae6524/WJCC-12-5821-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/4b8f036c10ef/WJCC-12-5821-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/e0ad6d779feb/WJCC-12-5821-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/007acd2c86d1/WJCC-12-5821-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/e0fb244a597b/WJCC-12-5821-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/6580118509b4/WJCC-12-5821-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/6cc383de58ab/WJCC-12-5821-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7912/11263061/e8feee2198f9/WJCC-12-5821-g008.jpg

相似文献

1
Severe acute pancreatitis complicated with intra-abdominal infection secondary to trauma: A case report.创伤后重症急性胰腺炎并发腹腔内感染：一例报告
World J Clin Cases. 2024 Sep 6;12(25):5821-5831. doi: 10.12998/wjcc.v12.i25.5821.
2
American Gastroenterological Association Clinical Practice Update: Management of Pancreatic Necrosis.美国胃肠病学会临床实践更新：胰腺坏死的处理。
Gastroenterology. 2020 Jan;158(1):67-75.e1. doi: 10.1053/j.gastro.2019.07.064. Epub 2019 Aug 31.
3
Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis.抗生素疗法预防急性胰腺炎胰腺坏死感染
Cochrane Database Syst Rev. 2003(4):CD002941. doi: 10.1002/14651858.CD002941.
4
[The therapeutic experience of blunt pancreatic trauma].钝性胰腺创伤的治疗经验
Zhonghua Wai Ke Za Zhi. 2019 Sep 1;57(9):660-665. doi: 10.3760/cma.j.issn.0529-5815.2019.09.004.
5
An Unusual Case of Isolated Pancreatitis Secondary to Blunt Abdominal Trauma.一例罕见的钝性腹部创伤继发孤立性胰腺炎病例。
Cureus. 2022 Mar 31;14(3):e23717. doi: 10.7759/cureus.23717. eCollection 2022 Mar.
6
Anterior abdominal abscess - a rare manifestation of severe acute pancreatitis: A case report.前腹壁脓肿——重症急性胰腺炎的罕见表现：一例报告
World J Clin Cases. 2021 Oct 26;9(30):9218-9227. doi: 10.12998/wjcc.v9.i30.9218.
7
Abdominal paracentesis drainage improves outcome of acute pancreatitis complicated with intra-abdominal hypertension in early phase.腹腔穿刺引流可改善早期急性胰腺炎合并腹腔内高压的预后。
Am J Med Sci. 2023 Jan;365(1):48-55. doi: 10.1016/j.amjms.2022.08.013. Epub 2022 Aug 27.
8
Conservative management of a case of traumatic pancreatitis in childhood: a case report.儿童创伤性胰腺炎1例的保守治疗：病例报告
Eur Rev Med Pharmacol Sci. 2014;18(12):1687-9.
9
Percutaneous endoscopic necrosectomy in a patient with emphysematous pancreatitis: A case report.经皮内镜下坏死组织清除术治疗气肿性胰腺炎 1 例报告。
Medicine (Baltimore). 2021 Nov 19;100(46):e27905. doi: 10.1097/MD.0000000000027905.
10
Acute pancreatitis associated with everolimus after kidney transplantation: a case report.肾移植后依维莫司相关的急性胰腺炎：一例报告
BMC Nephrol. 2016 Oct 28;17(1):163. doi: 10.1186/s12882-016-0376-6.

引用本文的文献

1
Acute pancreatitis secondary to small-cell lung cancer metastasis: A case report and literature review.小细胞肺癌转移继发急性胰腺炎：一例报告及文献复习
World J Clin Cases. 2025 Sep 26;13(27):107805. doi: 10.12998/wjcc.v13.i27.107805.
2
Targeting PFKFB3 to restore glucose metabolism in acute pancreatitis via nanovesicle delivery.通过纳米囊泡递送靶向磷酸果糖激酶-2/果糖-2,6-二磷酸酶3以恢复急性胰腺炎中的葡萄糖代谢。
Mol Med. 2025 Jul 5;31(1):253. doi: 10.1186/s10020-025-01261-y.

本文引用的文献

1
Timing of surgical operation for patients with intra-abdominal infection: A systematic review and meta-analysis.腹腔内感染患者手术时机：一项系统评价与荟萃分析
World J Gastrointest Surg. 2023 Oct 27;15(10):2320-2330. doi: 10.4240/wjgs.v15.i10.2320.
2
Management of Intra-Abdominal Infections: The Role of Procalcitonin.腹腔内感染的管理：降钙素原的作用
Antibiotics (Basel). 2023 Sep 4;12(9):1406. doi: 10.3390/antibiotics12091406.
3
WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections.
WSES/GAIS/SIS-E/WSIS/AAST 全球腹腔内感染患者临床路径。
World J Emerg Surg. 2021 Sep 25;16(1):49. doi: 10.1186/s13017-021-00387-8.
4
Duodeno-pancreatic and extrahepatic biliary tree trauma: WSES-AAST guidelines.十二指肠-胰腺和肝外胆道树创伤：WSES-AAST 指南。
World J Emerg Surg. 2019 Dec 11;14:56. doi: 10.1186/s13017-019-0278-6. eCollection 2019.
5
Traumatic pancreatitis.创伤性胰腺炎。
Abdom Radiol (NY). 2020 May;45(5):1265-1276. doi: 10.1007/s00261-019-02241-7.
6
A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway.《关于在手术全程合理使用抗菌药物的全球宣言》
Surg Infect (Larchmt). 2017 Nov/Dec;18(8):846-853. doi: 10.1089/sur.2017.219.
7
Abdominal sepsis.腹部脓毒症。
Curr Opin Crit Care. 2017 Apr;23(2):159-166. doi: 10.1097/MCC.0000000000000388.
8
The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection.外科感染学会关于腹腔内感染管理的修订指南。
Surg Infect (Larchmt). 2017 Jan;18(1):1-76. doi: 10.1089/sur.2016.261.
9
Pancreatic trauma: Management and literature review.胰腺创伤：治疗与文献综述
Cir Esp. 2017 Mar;95(3):123-130. doi: 10.1016/j.ciresp.2016.05.011. Epub 2016 Aug 12.
10
Management of splenic and pancreatic trauma.脾和胰腺创伤的管理。
J Visc Surg. 2016 Aug;153(4 Suppl):45-60. doi: 10.1016/j.jviscsurg.2016.04.005. Epub 2016 Jul 9.