基于超连续谱的超高分辨率内窥光学相干断层扫描成像的最佳操作条件
Optimal operational conditions for supercontinuum-based ultrahigh-resolution endoscopic OCT imaging.
作者信息
Yuan Wu, Mavadia-Shukla Jessica, Xi Jiefeng, Liang Wenxuan, Yu Xiaoyun, Yu Shaoyong, Li Xingde
出版信息
Opt Lett. 2016 Jan 15;41(2):250-3. doi: 10.1364/OL.41.000250.
Abstract
We investigated the optimal operational conditions for utilizing a broadband supercontinuum (SC) source in a portable 800 nm spectral-domain (SD) endoscopic OCT system to enable high resolution, high-sensitivity, and high-speed imaging in vivo. A SC source with a 3-dB bandwidth of ∼246 nm was employed to obtain an axial resolution of ∼2.7 μm (in air) and an optimal detection sensitivity of ∼-107 dB with an imaging speed up to 35 frames/s (at 70 k A-scans/s). The performance of the SC-based SD-OCT endoscopy system was demonstrated by imaging guinea pig esophagus in vivo, achieving image quality comparable to that acquired with a broadband home-built Ti:sapphire laser.
摘要
我们研究了在便携式800纳米光谱域（SD）内窥光学相干断层扫描（OCT）系统中利用宽带超连续谱（SC）光源的最佳操作条件，以实现体内高分辨率、高灵敏度和高速成像。采用一个3分贝带宽约为246纳米的SC光源，以获得约2.7微米（空气中）的轴向分辨率和约-107分贝的最佳检测灵敏度，成像速度高达35帧/秒（70千次A线扫描/秒）。基于SC的SD-OCT内窥镜系统的性能通过对豚鼠食管进行体内成像得到了证明，获得的图像质量与使用宽带自制钛宝石激光器获得的图像质量相当。
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