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基于动量的哑铃训练对轻度认知障碍老年人认知功能的影响:一项前瞻性随机对照试验。

Effects of momentum-based dumbbell training on cognitive function in older adults with mild cognitive impairment: a pilot randomized controlled trial.

作者信息

Lü Jiaojiao, Sun Mingyun, Liang Leichao, Feng Yi, Pan Xiaoyu, Liu Yu

机构信息

Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, People's Republic of China.

Institue of Physical Education, Anqing Normal University, Anqing, People's Republic of China; Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei, People's Republic of China.

出版信息

Clin Interv Aging. 2015 Dec 22;11:9-16. doi: 10.2147/CIA.S96042. eCollection 2016.

Abstract

PURPOSE

The purpose of this study was to explore the effects of an innovative momentum-based dumbbell-training intervention on cognitive function in older adults with mild cognitive impairment (MCI).

SUBJECTS AND METHODS

A total of 45 community-dwelling older adults with MCI were randomly assigned to either a dumbbell-training group (DTG; n=22) or a control group (CG; n=23). Participants in the DTG participated in exercise sessions three times weekly for 12 weeks. The primary outcome measures were cognitive function, including the Alzheimer's Disease Assessment Scale (ADAS) - Cognitive subscale, Trail Making Test part B, Digit Span Test (DST) - forward, and DST - backward, with secondary outcome measures being Timed Up and Go, functional reach, and the Activities-Specific Balance Confidence Scale.

RESULTS

In an intent-to-treat analysis, participants in the DTG had significantly improved ADAS - Cognitive subscale scores compared to those in the CG (5.02 points, P=0.012). There was a significant within-group change (improvement) in Trail Making Test part B (33.32 seconds, P<0.001) and DST - backward (0.41 points, P=0.025) scores. No change was observed for the DST - forward measure. Participants in the DTG also improved their functional mobility compared to those in the CG (Timed Up and Go, 0.81 seconds; P=0.043).

CONCLUSION

There is preliminary evidence showing the potential benefit of momentum-based dumbbell training for improving cognitive function in older adults with MCI.

摘要

目的

本研究旨在探讨一种基于动量的创新哑铃训练干预对轻度认知障碍(MCI)老年人认知功能的影响。

对象与方法

共有45名居住在社区的MCI老年人被随机分为哑铃训练组(DTG;n = 22)或对照组(CG;n = 23)。DTG组的参与者每周参加三次锻炼课程,共12周。主要结局指标为认知功能,包括阿尔茨海默病评估量表(ADAS)-认知分量表、连线测验B部分、数字广度测验(DST)-顺背和DST-倒背,次要结局指标为计时起立行走测试、功能性伸展和特定活动平衡信心量表。

结果

在意向性分析中,与CG组相比,DTG组参与者的ADAS-认知分量表得分显著提高(5.02分,P = 0.012)。连线测验B部分(33.32秒,P < 0.001)和DST-倒背(0.41分,P = 0.025)得分在组内有显著变化(改善)。DST-顺背测量未观察到变化。与CG组相比,DTG组参与者的功能性移动能力也有所改善(计时起立行走测试,0.81秒;P = 0.043)。

结论

有初步证据表明,基于动量的哑铃训练对改善MCI老年人的认知功能具有潜在益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6e8/4699540/c2391b0cfe3b/cia-11-009Fig1.jpg

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