Bentivegna Enrica, Morice Philippe, Uzan Catherine, Gouy Sebastien
Service de Chirurgie Gynécologique, Gustave-Roussy, 114 Rue Edouard-Vaillant, 94805 Villejuif Cedex, France.
Future Oncol. 2016 Feb;12(3):389-98. doi: 10.2217/fon.15.319. Epub 2016 Jan 15.
Since the last two decades, the feasibility of fertility-sparing surgery in early-stage epithelial ovarian cancer has been explored by several teams. Despite the impossibility of conducting a randomized trial to validate this management, evidence-based data suggest that in selected cases, the preservation of the uterus and at least one part of the ovary does not lead to a high risk of relapse. Conservative surgery maintains organ function, enables patients of childbearing age to preserve their fertility and improves their quality of life. In this review, we analyze the main series in the literature on this topic in order to highlight the selected criteria for conservative management and to summarize oncological and fertility outcomes.
在过去二十年中，多个团队对早期上皮性卵巢癌保留生育功能手术的可行性进行了探索。尽管无法通过随机试验来验证这种治疗方法，但循证数据表明，在特定病例中，保留子宫和至少一侧卵巢不会导致高复发风险。保守性手术可维持器官功能，使育龄患者能够保留生育能力并提高生活质量。在本综述中，我们分析了该主题文献中的主要系列研究，以突出保守治疗的选择标准，并总结肿瘤学和生育结局。
