Suppr超能文献

[确保生物样本库的可持续性]

[Securing the sustainability of biobanks].

作者信息

Kirsten Romy, Hummel Michael

机构信息

BioMaterialBank Heidelberg (BMBH), Universitätsklinikum Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Deutschland.

Charité, Universitätsmedizin Berlin, Berlin, Deutschland.

出版信息

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Mar;59(3):390-5. doi: 10.1007/s00103-015-2302-7.

Abstract

Active research sites in biomedicine need professionally structured, sustainable biobanks that represent established resources and technology platforms across different locations and disciplines. Currently, the funding of research biobanks is not uniformly regulated, mainly because of the different focuses, services and concepts. On the other hand, the samples and associated data of biobanks gain significant value over time, and therefore their long-term storage should be envisaged right from the start.The sustainability of biobank structures can be viewed from various perspectives, but financial sustainability certainly represents the most demanding challenge. The financing of biobanks can be achieved by a well-balanced model consisting of institutional resources and other funding sources such as infrastructure and research projects, complemented by reimbursement. Structural measures such as the creation of centralized biobank structures and involvement in consortia and networks contribute to the long-term use and exchange of samples across biobanks. In turn, a quality-controlled and transparent documentation of all processes and structures is required, which guarantees the utilization of the sparse financial resources for the most efficient use of the precious resource of human biomaterial. The long-term goal is the sustainable financing of an infrastructure that is essential for any modern biomedical research and provides benefit for the society.

摘要

活跃的生物医学研究机构需要专业构建、可持续发展的生物样本库,这些样本库代表着不同地点和学科的既有资源和技术平台。目前,研究用生物样本库的资金管理并不统一,主要原因在于关注点、服务内容和理念各不相同。另一方面,生物样本库的样本及相关数据会随着时间推移而大幅增值,因此从一开始就应考虑对其进行长期保存。生物样本库结构的可持续性可以从多个角度来看待,但财务可持续性无疑是最具挑战性的。生物样本库的资金筹集可以通过一种均衡的模式来实现,该模式包括机构资源以及其他资金来源,如基础设施和研究项目,并辅以费用报销。诸如创建集中式生物样本库结构以及参与联盟和网络等结构性措施,有助于生物样本库之间样本的长期使用和交换。反过来,需要对所有流程和结构进行质量控制且透明的记录,这能确保将稀缺的财务资源用于最有效地利用人类生物材料这一珍贵资源。长期目标是为任何现代生物医学研究必不可少且能造福社会的基础设施提供可持续的资金支持。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验