Chaddha Ashish, Eagle Kim A, Braverman Alan C, Kline-Rogers Eva, Hirsch Alan T, Brook Robert, Jackson Elizabeth A, Woznicki Elise M, Housholder-Hughes Susan, Pitler Linda, Franklin Barry A
Cardiovascular Center, University of Michigan, Ann Arbor, Michigan.
Cardiovascular Division, Washington University, St. Louis, Missouri.
Clin Cardiol. 2015 Nov;38(11):647-51. doi: 10.1002/clc.22481.
Despite the paucity of evidence, it is often presumed, and is physiologically plausible, that sudden, acute elevations in blood pressure may transiently increase the risk of recurrent aortic dissection (AD) or rupture in patients with a prior AD, because a post-dissection aorta is almost invariably dilated and may thus experience greater associated wall stress as compared with a nondilated aorta. Few data are available regarding the specific types and intensities of exercise that may be both safe and beneficial for this escalating patient population. The purpose of this editorial/commentary is to further explore this conundrum for clinicians caring for and counseling AD survivors. Moderate-intensity cardiovascular activity may be cardioprotective in this patient cohort. It is likely that severe physical activity restrictions may reduce functional capacity and quality of life in post-AD patients and thus be harmful, underscoring the importance of further exploring the role of physical activity and/or structured exercise in this at-risk patient population.
尽管证据不足,但人们常常假定,且从生理角度来看也有其合理性,即血压突然急剧升高可能会短暂增加既往有主动脉夹层(AD)患者复发主动脉夹层或破裂的风险,因为夹层后的主动脉几乎总是扩张的,因此与未扩张的主动脉相比,可能承受更大的相关壁应力。关于哪些特定类型和强度的运动对这一不断增加的患者群体既安全又有益,目前几乎没有相关数据。这篇社论/评论的目的是为照顾和咨询AD幸存者的临床医生进一步探讨这一难题。中等强度的心血管活动可能对这一患者群体具有心脏保护作用。严格限制体力活动可能会降低AD后患者的功能能力和生活质量,从而产生有害影响,这突出了进一步探索体力活动和/或结构化运动在这一高危患者群体中的作用的重要性。