Chaddha Ashish, Kline-Rogers Eva, Braverman Alan C, Erickson Steven R, Jackson Elizabeth A, Franklin Barry A, Woznicki Elise M, Jabara Justin T, Montgomery Daniel G, Eagle Kim A
Cardiovascular Center, University of Michigan, Ann Arbor, Michigan.
Cardiovascular Division, Washington University, St. Louis, Missouri.
Clin Cardiol. 2015 Nov;38(11):652-9. doi: 10.1002/clc.22418.
Currently no research exists assessing lifestyle modifications and emotional state of acute aortic dissection (AAD) survivors. We sought to assess activity, mental health, and sexual function in AAD survivors.
Physical and sexual activity will decrease in AAD survivors compared to pre-dissection. Incidence of anxiety and depression will be significant after AAD.
A cross sectional survey was mailed to 197 subjects from a single academic medical center (part of larger IRAD database). Subjects were ≥18 years of age surviving a type A or B AAD between 1996 and 2011. 82 surveys were returned (overall response rate 42%).
Mean age ± SD was 59.5 ± 13.7 years, with 54.9% type A and 43.9% type B patients. Walking remained the most prevalent form of physical activity (49 (60%) pre-dissection and 47 (57%) post-dissection). Physical inactivity increased from 14 (17%) before AAD to 20 (24%) after AAD; sexual activity decreased from 31 (38%) to 9 (11%) mostly due to fear. Most patients (66.7%) were not exerting themselves physically or emotionally at AAD onset. Systolic blood pressure (SBP) at 36 months post-discharge for patients engaging in ≥2 sessions of aerobic activity/week was 126.67 ± 10.30 vs. 141.10 ± 11.87 (p-value 0.012) in those who did not. Self-reported new-onset depression after AAD was 32% and also 32% for new-onset anxiety.
Alterations in lifestyle and emotional state are frequent in AAD survivors. Clinicians should screen for unfounded fears or beliefs after dissection that may reduce function and/or quality of life for AAD survivors.
目前尚无关于急性主动脉夹层(AAD)幸存者生活方式改变和情绪状态的研究。我们试图评估AAD幸存者的活动情况、心理健康状况和性功能。
与发病前相比,AAD幸存者的身体活动和性活动将会减少。AAD后焦虑和抑郁的发生率将会显著升高。
向来自单一学术医疗中心(大型国际急性主动脉夹层注册研究[IRAD]数据库的一部分)的197名受试者邮寄了一份横断面调查问卷。受试者为1996年至2011年间存活的年龄≥18岁的A型或B型AAD患者。共返回82份调查问卷(总体回复率42%)。
平均年龄±标准差为59.5±13.7岁,其中A型患者占54.9%,B型患者占43.9%。步行仍然是最常见的身体活动形式(发病前49例[60%],发病后47例[57%])。身体不活动的情况从AAD前的14例(17%)增加到AAD后的20例(24%);性活动从31例(38%)减少到9例(11%),主要原因是恐惧。大多数患者(66.7%)在AAD发病时身体或情绪上并未过度劳累。每周进行≥2次有氧运动的患者出院后36个月时的收缩压(SBP)为126.67±10.30,而未进行有氧运动的患者为141.10±11.87(p值0.012)。AAD后自我报告的新发抑郁症发生率为32%,新发焦虑症发生率也为32%。
AAD幸存者的生活方式和情绪状态经常发生改变。临床医生应筛查发病后可能会降低AAD幸存者功能和/或生活质量的无端恐惧或信念。