Zou Chunpeng, Jiao Yan, Zheng Chao, Zhao Yaping, Li Xingwang
Department of Ultrasonic Diagnosis, Second Affiliated Hospital & Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China (mainland).
Department of Obstetrics and Gynecology Ultrasonic, Wenzhou City Peoples' Hospital, Wenzhou, China (mainland).
Med Sci Monit. 2014 Nov 24;20:2414-20. doi: 10.12659/MSM.891093.
The aim of this study was to investigate the feasibility and value of strain-blood pressure index (SBPI) to assess early changes in elasticity of anterior tibial artery in patients with type 2 diabetes mellitus (T2DM).
MATERIAL/METHODS: Eighty-one randomly selected in-patients with T2DM were divided into 2 groups--a vascular complication negative group (n=42) and a vascular complication positive group (n=39). Forty healthy volunteers were enrolled in a control group. Ultrasonographic scans using Xstrain™ technique were conducted for every patient to obtain the maximum circumferential strain (CSmax) of anterior tibial artery; patient blood pressure was also measured for calculating strain-blood pressure index (SBPI=CSmax/[(local pulse pressure)/local diastolic blood pressure] ×100%. Afterwards, SBPIs of various groups were comparatively analyzed.
Differences in SBPIs among the 3 groups were statistically significant (control group > negative group > positive group, P<0.05).
SBPI could be used as a new indicator for the evaluation on the anterior tibial arterial elasticity of T2DM patients and it was able to reflect the early elasticity changes in anterior tibial arteries in T2DM patients with atherosclerosis.
本研究旨在探讨应变-血压指数（SBPI）评估2型糖尿病（T2DM）患者胫前动脉弹性早期变化的可行性和价值。
材料/方法：随机选取81例T2DM住院患者，分为2组——血管并发症阴性组（n = 42）和血管并发症阳性组（n = 39）。40名健康志愿者纳入对照组。对每位患者采用Xstrain™技术进行超声扫描，以获取胫前动脉的最大圆周应变（CSmax）；同时测量患者血压以计算应变-血压指数（SBPI = CSmax / [（局部脉压）/局部舒张压]×100%）。之后，对各组的SBPI进行比较分析。
3组间SBPI差异有统计学意义（对照组>阴性组>阳性组，P < 0.05）。
SBPI可作为评估T2DM患者胫前动脉弹性的新指标，能够反映T2DM合并动脉粥样硬化患者胫前动脉的早期弹性变化。
