Zhang Liqing, Guo Xiuxia, Min Yongzheng, Xu Jianjiang
Department of Urology Surgery, General Hospital of Jinan Military Command Jinan, China.
Department of Gynecology, General Hospital of Jinan Military Command Jinan, China.
Int J Clin Exp Med. 2015 Oct 15;8(10):18528-32. eCollection 2015.
This study aims to investigate the application value of tumor abnormal protein (TAP) examination in the diagnosis of urothelial carcinoma of the bladder.
Abnormal sugar chain glycoproteins in the peripheral blood of 87 patients with urothelial carcinoma of the bladder were detected, and compared with non-tumor patients accompanied by hematuria.
TAP examination showed that the positive rate of the abnormal sugar chain glycoprotein in the peripheral blood of the 87 patients with urothelial carcinoma of the bladder was 78.16%, whereas that of the non-tumor patients was 10.81%. The former is significantly higher than the latter (P<0.01).
TAP examination can be used to detect urothelial carcinoma of the bladder, and would be helpful in the diagnosis of urothelial carcinoma of the bladder by combining the clinical signs and symptoms.
本研究旨在探讨肿瘤异常蛋白（TAP）检测在膀胱尿路上皮癌诊断中的应用价值。
检测87例膀胱尿路上皮癌患者外周血中的异常糖链糖蛋白，并与伴有血尿的非肿瘤患者进行比较。
TAP检测显示，87例膀胱尿路上皮癌患者外周血中异常糖链糖蛋白的阳性率为78.16%，而非肿瘤患者的阳性率为10.81%。前者显著高于后者（P<0.01）。
TAP检测可用于检测膀胱尿路上皮癌，结合临床症状和体征有助于膀胱尿路上皮癌的诊断。
