Liu Tao-Tao, Hong Qing-Xiong, Xiang Hong-Bing
Department of Anesthesiology and Pain Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, Hubei, PR China.
Department of Anesthesiology, Guangdong Provincial Hospital of Chinese Medicine Guangzhou 510120, PR China.
Int J Clin Exp Med. 2015 Oct 15;8(10):19481-5. eCollection 2015.
Some reports have demonstrated that deep brain stimulation (DBS) is a promising treatment for patients who suffer from intractable anorexia nervosa. However, the nature of DBS may not be viewed as a standard clinical treatment option for anorexia nervosa because of the unpredictable outcome before DBS. Just like DBS in the brain, electroacupuncture at acupoints is also efficient in treating refractory anorexia nervosa. Some neuroimaging studies using functional magnetic resonance imaging, single-photon emission computed tomography (SPECT), and positron emission tomography (PET) had revealed that both DBS and electroacupuncture at acupoints with electrical stimulation are related to the changes in cerebral glucose metabolism. Therefore, we hypothesize that the changes in cerebral glucose metabolism after electroacupuncture might be useful to predict the therapeutic effect of deep brain stimulation for refractory anorexia nervosa.
一些报告表明，深部脑刺激（DBS）对于患有难治性神经性厌食症的患者是一种有前景的治疗方法。然而，由于DBS之前的结果不可预测，其性质可能不被视为神经性厌食症的标准临床治疗选择。就像脑部的DBS一样，穴位电针在治疗难治性神经性厌食症方面也很有效。一些使用功能磁共振成像、单光子发射计算机断层扫描（SPECT）和正电子发射断层扫描（PET）的神经影像学研究表明，DBS和穴位电刺激都与脑葡萄糖代谢的变化有关。因此，我们假设电针后脑葡萄糖代谢的变化可能有助于预测深部脑刺激对难治性神经性厌食症的治疗效果。
