Vriz Olga, Driussi Caterina, La Carrubba Salvatore, Di Bello Vitantonio, Zito Concetta, Carerj Scipione, Antonini-Canterin Francesco
Cardiology and Emergency Department, San Antonio Hospital, San Daniele del Friuli, Udine, Italy.
School of Sports Medicine, University of Udine, Udine, Italy.
SAGE Open Med. 2013 Oct 8;1:2050312113507563. doi: 10.1177/2050312113507563. eCollection 2013.
Recently, echo-tracking-derived measures of arterial stiffness have been introduced in clinical practice for the assessment of one-point pulse wave velocity. The purpose of this study was to find a relation between carotid-femoral pulse wave velocity and one-point carotid pulse wave velocity, and to find a value of one-point carotid pulse wave velocity that predicts carotid-femoral pulse wave velocity higher than 12 m/s.
A total of 160 consecutive subjects (112 male/48 female, mean age = 51.5 ± 14.1 years; 96 healthy, 44 hypertensives, 13 with aortic valve disease, and 7 with left ventricular dysfunction) were studied. Carotid-femoral pulse wave velocity was measured with the SphygmoCor system and one-point carotid pulse wave velocity with high-definition echo-tracking system (ProSound Alpha10; Aloka, Tokyo, Japan).
Both carotid-femoral pulse wave velocity and one-point carotid pulse wave velocity correlated significantly with each other (r = 0.539, p < 0.001) and with age (one-point carotid pulse wave velocity r = 0.618, carotid-femoral pulse wave velocity r = 0.617, p < 0.0001 for both). Median value of carotid-femoral pulse wave velocity (7.2 m/s, 95% confidence interval = 6.2-8.9) was systematically higher than that of one-point carotid pulse wave velocity (5.8 m/s, 95% confidence interval = 5-6.6). The area under the receiver operating characteristic curve was 0.85, identifying the cutoff for one-point pulse wave velocity of 6.65 m/s as the best predictor of carotid-femoral pulse wave velocity more than 12 m/s (sensitivity = 0.818, specificity = 0.819).
One-point carotid pulse wave velocity correlates with carotid-femoral pulse wave velocity, and the cutoff of 6.65 m/s was the best predictor of carotid-femoral pulse wave velocity over 12 m/s.
最近，回声跟踪衍生的动脉僵硬度测量方法已被引入临床实践，用于评估单点脉搏波速度。本研究的目的是找出颈动脉-股动脉脉搏波速度与单点颈动脉脉搏波速度之间的关系，并找出一个能预测颈动脉-股动脉脉搏波速度高于12米/秒的单点颈动脉脉搏波速度值。
共研究了160名连续受试者（112名男性/48名女性，平均年龄=51.5±14.1岁；96名健康者，44名高血压患者，13名主动脉瓣疾病患者，7名左心室功能障碍患者）。使用SphygmoCor系统测量颈动脉-股动脉脉搏波速度，使用高清回声跟踪系统（ProSound Alpha10；日本东京阿洛卡公司）测量单点颈动脉脉搏波速度。
颈动脉-股动脉脉搏波速度和单点颈动脉脉搏波速度之间显著相关（r=0.539，p<0.001），且均与年龄相关（单点颈动脉脉搏波速度r=0.618，颈动脉-股动脉脉搏波速度r=0.617，两者p<0.0001）。颈动脉-股动脉脉搏波速度的中位数（7.2米/秒，95%置信区间=6.2-8.9）系统地高于单点颈动脉脉搏波速度的中位数（5.8米/秒，95%置信区间=5-6.6）。受试者工作特征曲线下面积为0.85，确定单点脉搏波速度6.65米/秒的截断值为颈动脉-股动脉脉搏波速度超过12米/秒的最佳预测指标（敏感性=0.818，特异性=0.819）。
单点颈动脉脉搏波速度与颈动脉-股动脉脉搏波速度相关，6.65米/秒的截断值是颈动脉-股动脉脉搏波速度超过12米/秒的最佳预测指标。
