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隐形眼镜相关微生物性角膜炎的临床表现及抗生素敏感性

Clinical Presentation and Antibiotic Susceptibility of Contact Lens Associated Microbial Keratitis.

作者信息

Hedayati Hesam, Ghaderpanah Mahboubeh, Rasoulinejad Seyed Ahmad, Montazeri Mohammad

机构信息

Department of Ophthalmology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Department of Ophthalmology, Babol University of Medical Sciences, Babol, Iran.

出版信息

J Pathog. 2015;2015:152767. doi: 10.1155/2015/152767. Epub 2015 Dec 3.

Abstract

Introduction. In recent years, the number of contact lens wearers has dramatically increased in Iran, particularly in youngsters. The purpose of current study was to assess the clinical presentation and antibiotic susceptibility of contact lens related microbial keratitis in Ahvaz, southwest of Iran. Methodology. A cross-sectional investigation of 26 patients (33 eyes) with contact lens induced corneal ulcers who were admitted to Imam Khomeini Hospital, Ahwaz City, from June 2012 to June 2013 was done. In order to study microbial culture and susceptibility of corneal ulcers, all of them were scraped. Results. Eight samples were reported as sterile. Pseudomonas aeruginosa (80%) in positive cultures was the most widely recognized causative organism isolated. This is followed by Staphylococcus aureus 12% and Enterobacter 8%. The results showed that 84% of the microorganism cases were sensitive to ciprofloxacin, while imipenem, meropenem, and ceftazidime were the second most effective antibiotics (76%). Conclusion. Results of current study show the importance of referring all contact lens wearers with suspected corneal infection to ophthalmologists for more cure. The corneal scraping culture and contact lens solution should be performed to guide antibiotic therapy.

摘要

引言。近年来,伊朗佩戴隐形眼镜的人数急剧增加,尤其是在年轻人当中。本研究的目的是评估伊朗西南部阿瓦士地区与隐形眼镜相关的微生物性角膜炎的临床表现及抗生素敏感性。方法。对2012年6月至2013年6月期间入住阿瓦士市伊玛目霍梅尼医院的26例(33只眼)隐形眼镜诱发角膜溃疡患者进行了横断面调查。为研究角膜溃疡的微生物培养及药敏情况,对所有患者进行了刮片检查。结果。8份样本报告为无菌。阳性培养物中铜绿假单胞菌(80%)是分离出的最常见致病微生物。其次是金黄色葡萄球菌(12%)和肠杆菌(8%)。结果显示,84%的微生物病例对环丙沙星敏感,而亚胺培南、美罗培南和头孢他啶是第二有效的抗生素(76%)。结论。本研究结果表明,所有疑似角膜感染的隐形眼镜佩戴者应转诊给眼科医生以进行更好的治疗。应进行角膜刮片培养及隐形眼镜护理液检查以指导抗生素治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b41/4681797/f11d16a2597a/JPATH2015-152767.001.jpg

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