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代谢组学技术在提高食品质量方面的应用:实践与前景。

Metabolomic Technologies for Improving the Quality of Food: Practice and Promise.

机构信息

USDA-ARS, SEA Food Science Research Unit, North Carolina State University, Raleigh, North Carolina, 27695; email:

Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, North Carolina 27695-7624; email:

出版信息

Annu Rev Food Sci Technol. 2016;7:413-38. doi: 10.1146/annurev-food-022814-015721. Epub 2016 Jan 11.

Abstract

It is now well documented that the diet has a significant impact on human health and well-being. However, the complete set of small molecule metabolites present in foods that make up the human diet and the role of food production systems in altering this food metabolome are still largely unknown. Metabolomic platforms that rely on nuclear magnetic resonance (NMR) and mass spectrometry (MS) analytical technologies are being employed to study the impact of agricultural practices, processing, and storage on the global chemical composition of food; to identify novel bioactive compounds; and for authentication and region-of-origin classifications. This review provides an overview of the current terminology, analytical methods, and compounds associated with metabolomic studies, and provides insight into the application of metabolomics to generate new knowledge that enables us to produce, preserve, and distribute high-quality foods for health promotion.

摘要

现在有充分的证据表明,饮食对人类的健康和幸福有重大影响。然而,构成人类饮食的食物中存在的完整的小分子代谢物组,以及食品生产系统在改变这种食物代谢组方面的作用,在很大程度上仍然未知。代谢组学平台依赖于核磁共振(NMR)和质谱(MS)分析技术,用于研究农业实践、加工和储存对食物全球化学成分的影响;鉴定新的生物活性化合物;以及用于认证和原产地分类。这篇综述概述了代谢组学研究中当前的术语、分析方法和相关化合物,并深入探讨了代谢组学在产生新知识方面的应用,这些新知识使我们能够生产、保存和分发促进健康的高质量食品。

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