Department of Psychology, University of Texas at Austin, 1 University Station, A8000 Austin, TX 78712, USA.
Department of Psychology, University of Texas at Austin, 1 University Station, A8000 Austin, TX 78712, USA.
Trends Neurosci. 2016 Feb;39(2):51-53. doi: 10.1016/j.tins.2015.12.010. Epub 2016 Jan 6.
Pavlovian fear conditioning is one of the most common and well-understood methods for studying fear learning. However, research is predominantly performed in males. Recently, in a classical Pavlovian fear conditioning paradigm, Gruene and colleagues described an active conditioned fear response ('darting') prevalent in female rats that better maintain an extinction memory.
巴甫洛夫式恐惧条件反射是研究恐惧学习最常用和最被理解的方法之一。然而,研究主要是在雄性动物中进行的。最近,在一个经典的巴甫洛夫式恐惧条件反射范式中,Gruene 和同事描述了一种在雌性大鼠中普遍存在的活跃的条件性恐惧反应(“猛冲”),这种反应更能维持消退记忆。