Aldridge Beau, Ladd Alan P, Kepple Jacqueline, Wingle Teresa, Ring Christopher, Kokoska Evan R
Department of Pediatric Surgery, Peyton Manning Children's Hospital, 2001 W 86th St., Indianapolis, IN, 46260, USA.
Department of Surgery, School of Medicine, Indiana University, Riley Hospital for Children, Indianapolis, IN, USA.
Am J Surg. 2016 Mar;211(3):605-9. doi: 10.1016/j.amjsurg.2015.11.009. Epub 2015 Dec 23.
Current treatment of giant omphalocele includes "paint and wait" or placement of mesh or silo. These methods are associated with high complication rates. We propose negative pressure wound therapy as an alternative.
Patients born between 2009 and 2014 with giant omphalocele were included. Outcomes analyzed were duration of therapy, time to full enteral feeds, treatment related complications, wound surface area over time, type, and time to definitive closure.
Eight patients were reviewed. The median duration of therapy was 68 days. Median time to full enteral feeds was 19 days. There were no treatment discontinuations or complications including sac ruptures, wound infections, or fistulas. Wound contraction stopped at 2 months or around 7 cm(2). All surviving patients underwent definitive closure.
Negative pressure wound therapy is a safe and effective treatment for giant omphalocele that allows feeding, has a low complication rate, and is completed in 2 months.
目前巨大脐膨出的治疗方法包括“涂抹并等待”或放置补片或使用脐膨出袋。这些方法并发症发生率高。我们提出负压伤口治疗作为一种替代方法。
纳入2009年至2014年出生的巨大脐膨出患者。分析的结果包括治疗持续时间、完全经肠喂养时间、治疗相关并发症、伤口表面积随时间的变化、类型以及确定性闭合的时间。
对8例患者进行了回顾。治疗的中位持续时间为68天。完全经肠喂养的中位时间为19天。没有治疗中断或并发症，包括囊破裂、伤口感染或瘘管。伤口收缩在2个月或约7平方厘米时停止。所有存活患者均接受了确定性闭合。
负压伤口治疗是一种安全有效的巨大脐膨出治疗方法，可实现喂养，并发症发生率低，并在2个月内完成治疗。
