养老院中痴呆患者的身体约束和抗精神病药物使用。
Physical Restraint and Antipsychotic Medication Use Among Nursing Home Residents With Dementia.
机构信息
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Centro Medicina dell'Invecchiamento, Università Cattolica del Sacro Cuore, Rome, Italy.
Centro Medicina dell'Invecchiamento, Università Cattolica del Sacro Cuore, Rome, Italy.
出版信息
J Am Med Dir Assoc. 2016 Feb;17(2):184.e9-14. doi: 10.1016/j.jamda.2015.11.014. Epub 2016 Jan 6.
PURPOSE
To explore antipsychotic (AP) medications and physical restraint use and their effects on physical function and cognition in older nursing home residents.
METHODS
This retrospective cohort studied involved 532 residents with dementia from 57 nursing homes participating in the Services and Health for Elderly in Long-Term Care study. Poisson log regression models explored the effect of physical restraint and/or AP medication use on cognitive or functional decline at 6 months.
RESULTS
Physical restraint use was associated with a higher risk of both functional and cognitive decline compared with AP medication use alone. These risks were highest among residents receiving both AP medications and physical restraints, suggesting additive effects.
DISCUSSION
Physical restraint use, and even more strongly, concurrent physical restraint and AP medication use, is related to function and cognitive decline in nursing home residents with dementia. Antipsychotic use is cautioned, but these results suggest physical restraint use is potentially more risky.
目的
探讨抗精神病药物（AP）和身体约束的使用及其对老年疗养院居民身体功能和认知的影响。
方法
这项回顾性队列研究涉及来自参与长期护理服务和健康老龄化研究的 57 家疗养院的 532 名痴呆症患者。泊松对数回归模型探讨了身体约束和/或 AP 药物使用对 6 个月时认知或功能下降的影响。
结果
与单独使用 AP 药物相比，身体约束的使用与功能和认知下降的风险更高。在同时接受 AP 药物和身体约束的居民中，这些风险最高，表明存在附加效应。
讨论
身体约束的使用，甚至更强烈的是，同时使用身体约束和 AP 药物与痴呆疗养院居民的功能和认知下降有关。使用抗精神病药物是有风险的，但这些结果表明身体约束的使用可能更具风险。
Zotero 插件