Zare Sajad, Nassiri Parvin, Monazzam Mohammad Reza, Pourbakht Akram, Azam Kamal, Golmohammadi Taghi
Department of Occupational Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Noise Health. 2016 Jan-Feb;18(80):1-6. doi: 10.4103/1463-1741.174358.
The existing literature indicates that occupational exposure to noise may have adverse effects on workers' health. The aim of this study was to evaluate the possible effects of exposure to different sound pressure levels (SPLs) on serum aldosterone and potassium concentration among Iranian blue collar workers in Golgohar Mining and Industrial Company in Sirjan, Kerman Province, Iran. This case-control study was performed on 45 workers of Golgohar Mining and Industrial Company. The subjects consisted of 30 workers from manufacturing departments and 15 office employees of the mining company. The controls, mainly with administrative jobs were exposed to 72 dBA SPL. Cases, in two separate groups, were exposed to noise levels of 88 dBA and 103 dBA, respectively. Noise intensity was measured at the desired locations. Noise measurements were performed according to the International Organization for Standardization (ISO) 9612. To measure the serum aldosterone and potassium concentrations, a 5 mL blood sample was taken from each worker at the specified time intervals and aldosterone concentration was determined using enzyme-linked immunosorbent assay (ELISA) test in the laboratory. Repeated measurement and Spearman's correlation coefficient analysis were used with α = 0.05. Exposure to the different levels of sound pressure resulted in different aldosterone concentrations and meanwhile an increase in the SPL did not affect the concentration of potassium. From 10:00 AM to 10:30 AM, as SPL increased, aldosterone concentrations did not increase significantly but from 13:30 PM to 14:00 PM, raised SPL led to a significant increase in aldosterone concentration. However, there was no correlation between the concentration of potassium and different factors. This study indicated that increases in SPLs affect aldosterone concentration but at the same time do not have significant effects on serum potassium level.
现有文献表明，职业性噪声暴露可能对工人健康产生不利影响。本研究的目的是评估伊朗克尔曼省锡尔詹市戈尔戈哈尔矿业和工业公司不同声压级（SPL）暴露对伊朗蓝领工人血清醛固酮和钾浓度的可能影响。本病例对照研究在戈尔戈哈尔矿业和工业公司的45名工人中进行。研究对象包括制造部门的30名工人和该矿业公司的15名办公室员工。对照组主要从事行政工作，暴露于72分贝A声压级。病例分为两组，分别暴露于88分贝A和103分贝A的噪声水平。在所需位置测量噪声强度。噪声测量按照国际标准化组织（ISO）9612进行。为了测量血清醛固酮和钾浓度，在规定的时间间隔从每名工人采集5毫升血样，并在实验室使用酶联免疫吸附测定（ELISA）试验测定醛固酮浓度。采用重复测量和Spearman相关系数分析，α = 0.05。暴露于不同声压水平导致醛固酮浓度不同，同时声压级的增加并未影响钾的浓度。从上午10:00到上午10:30，随着声压级增加，醛固酮浓度没有显著增加，但从下午13:30到下午14:00，声压级升高导致醛固酮浓度显著增加。然而，钾浓度与不同因素之间没有相关性。本研究表明，声压级的增加会影响醛固酮浓度，但同时对血清钾水平没有显著影响。
