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本文引用的文献

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Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline.小肠胶囊内镜检查和器械辅助小肠镜检查在小肠疾病诊断和治疗中的应用:欧洲胃肠内镜学会(ESGE)临床指南
Endoscopy. 2015 Apr;47(4):352-76. doi: 10.1055/s-0034-1391855. Epub 2015 Mar 31.
2
Management of gastrointestinal angiodysplastic lesions (GIADs): a systematic review and meta-analysis.胃肠道血管发育不良病变(GIADs)的管理:系统评价和荟萃分析。
Am J Gastroenterol. 2014 Apr;109(4):474-83; quiz 484. doi: 10.1038/ajg.2014.19. Epub 2014 Mar 18.
3
Review article: gastrointestinal angiodysplasia - pathogenesis, diagnosis and management.综述文章:胃肠道血管发育不良 - 发病机制、诊断和治疗。
Aliment Pharmacol Ther. 2014 Jan;39(1):15-34. doi: 10.1111/apt.12527. Epub 2013 Oct 20.
4
Efficacy of thalidomide for refractory gastrointestinal bleeding from vascular malformation.反应停治疗血管畸形所致难治性胃肠道出血的疗效。
Gastroenterology. 2011 Nov;141(5):1629-37.e1-4. doi: 10.1053/j.gastro.2011.07.018. Epub 2011 Jul 22.
5
Increased expression of angiogenic factors in human colonic angiodysplasia.人类结肠血管发育异常中血管生成因子表达增加。
Am J Gastroenterol. 1999 Apr;94(4):1070-6. doi: 10.1111/j.1572-0241.1999.01017.x.
6
Angiodysplasia as a cause of upper gastrointestinal bleeding.
Arch Intern Med. 1985 Mar;145(3):458-61.
7
On the nature and etiology of vascular ectasias of the colon. Degenerative lesions of aging.
Gastroenterology. 1977 Apr;72(4 Pt 1):650-60.

沙利度胺用于治疗一名急性上消化道出血患者的血管发育异常。

Thalidomide for the treatment of angiodysplasia in a patient with acute upper gastrointestinal haemorrhage.

作者信息

Bond Adam, Ahmed Waqar

机构信息

Department of Wales Deanery, Cardiff University, Cardiff, UK Ysbyty Gwynedd, Bangor, Gwynedd, UK.

Department of Gastroenterology, Ysbyty Gwynedd, Bangor, Gwynedd, UK.

出版信息

BMJ Case Rep. 2016 Jan 20;2016:bcr2015213522. doi: 10.1136/bcr-2015-213522.

DOI:10.1136/bcr-2015-213522
PMID:26791122
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4735386/
Abstract

Gastrointestinal (GI) angiodysplasia is an important and challenging cause of acute GI haemorrhage, particularly in the elderly. We present the case of an 83-year-old woman admitted with acute upper GI bleeding that was refractory to both endoscopic ablation with argon plasma coagulation and gastroduodenal artery embolisation. Administration of thalidomide 100 mg daily after failure of the above therapeutic procedures resulted in cessation of bleeding and avoided the need for further blood transfusion at 6-month follow-up.

摘要

胃肠道血管发育异常是急性胃肠道出血的一个重要且具有挑战性的原因,尤其是在老年人中。我们报告了一例83岁女性患者,因急性上消化道出血入院,氩离子凝固术内镜消融和胃十二指肠动脉栓塞治疗均无效。在上述治疗程序失败后,每天给予100毫克沙利度胺,出血停止,在6个月的随访中无需进一步输血。