沙利度胺用于治疗一名急性上消化道出血患者的血管发育异常。
Thalidomide for the treatment of angiodysplasia in a patient with acute upper gastrointestinal haemorrhage.
作者信息
Bond Adam, Ahmed Waqar
机构信息
Department of Wales Deanery, Cardiff University, Cardiff, UK Ysbyty Gwynedd, Bangor, Gwynedd, UK.
Department of Gastroenterology, Ysbyty Gwynedd, Bangor, Gwynedd, UK.
出版信息
BMJ Case Rep. 2016 Jan 20;2016:bcr2015213522. doi: 10.1136/bcr-2015-213522.
Abstract
Gastrointestinal (GI) angiodysplasia is an important and challenging cause of acute GI haemorrhage, particularly in the elderly. We present the case of an 83-year-old woman admitted with acute upper GI bleeding that was refractory to both endoscopic ablation with argon plasma coagulation and gastroduodenal artery embolisation. Administration of thalidomide 100 mg daily after failure of the above therapeutic procedures resulted in cessation of bleeding and avoided the need for further blood transfusion at 6-month follow-up.
摘要
胃肠道血管发育异常是急性胃肠道出血的一个重要且具有挑战性的原因，尤其是在老年人中。我们报告了一例83岁女性患者，因急性上消化道出血入院，氩离子凝固术内镜消融和胃十二指肠动脉栓塞治疗均无效。在上述治疗程序失败后，每天给予100毫克沙利度胺，出血停止，在6个月的随访中无需进一步输血。
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