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焦虑与跌倒的关联:一项荟萃分析。

The Association Between Anxiety and Falls: A Meta-Analysis.

机构信息

Institute for Health and Ageing, Australian Catholic University, Melbourne, Victoria.

出版信息

J Gerontol B Psychol Sci Soc Sci. 2017 Sep 1;72(5):729-741. doi: 10.1093/geronb/gbv160.

Abstract

OBJECTIVES

Falls occur frequently among older adults and can lead to a range of adverse and debilitating outcomes. Although symptoms of clinical anxiety have been implicated as risk factors for falls, there is no current consensus on the empirical association between anxiety and falls. The current study aimed to address this gap in the literature by conducting a quantitative, meta-analytic review of findings from previous studies.

METHOD

A systematic literature search of bibliographic databases was conducted, yielding 18 studies that fit the criteria for inclusion in the meta-analysis.

RESULTS

A random-effects model of all 18 studies showed a significant overall odds ratio of 1.53 (95% CI 1.28-1.83, p < .001), indicating that elevated levels of anxiety were associated with a 53% increased likelihood of falls. A high amount of variance among effect sizes was observed. Only age was identified as a moderator of this relationship in a subgroup of the samples.

CONCLUSIONS

Clinical anxiety is associated with falls, however, further research is required to elucidate the factors that might moderate or mediate this relationship, the casual pathways through which they are related, and the associations between different types of anxiety and falls.

摘要

目的

老年人经常会发生跌倒,跌倒会导致一系列不良和虚弱的后果。尽管临床焦虑症状被认为是跌倒的危险因素,但目前对于焦虑与跌倒之间的实证关联尚无共识。本研究旨在通过对以往研究结果进行定量、荟萃分析来填补这一文献空白。

方法

对文献数据库进行系统的文献检索,共纳入了 18 项符合纳入标准的研究进行荟萃分析。

结果

对所有 18 项研究的随机效应模型显示,整体优势比为 1.53(95%置信区间 1.28-1.83,p<0.001),表明焦虑水平升高与跌倒的可能性增加 53%相关。研究间效应大小的差异很大。仅在样本的亚组中发现年龄是该关系的调节因素。

结论

临床焦虑与跌倒有关,然而,还需要进一步研究来阐明可能调节或中介这种关系的因素、它们相关的因果途径以及不同类型的焦虑与跌倒之间的关联。

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