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老年人复发性跌倒的危险因素:系统评价和荟萃分析的研究方案。

Risk factors for recurrent falls in older adults: a study protocol for a systematic review with meta-analysis.

机构信息

Djavad Mowafaghian Centre for Brain Health, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.

Centre for Hip Health and Mobility, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.

出版信息

BMJ Open. 2020 May 5;10(5):e033602. doi: 10.1136/bmjopen-2019-033602.

Abstract

INTRODUCTION

Older adults who fall recurrently (i.e., >1 fall/year) are at risk for functional decline and mortality. Key risk factors for recurrent falls in community-dwelling older adults are not well established due to methodological limitations, such as recall bias. A better understanding of the risk factors for recurrent falls will aid in refining clinical practice guidelines for secondary fall prevention strategies. The primary objective of this systematic review with meta-analysis is to examine the risk factors for recurrent falls in prospective studies among community-dwelling older adults.

METHODS AND ANALYSIS

A comprehensive search for articles indexed in MEDLINE, EMBASE, PsycINFO and CINAHL databases as well as grey literature was conducted on April 25, 2019. We will use MeSH and keyword search terms around the following topics: falls, recurrence, fall-risk, ageing and prospective studies. Prospective studies with monthly falls monitoring for 12 months, investigating risk factors for recurrent falls in older adults will be included. One author will complete the search. Two authors will remove duplicates and screen the titles and abstracts for their potential inclusion against the eligibility criteria. Two authors will screen the full texts and extract the data using a piloted extraction sheet. Included studies will be evaluated for the risk of bias with the Joanna Briggs Institute Prevalence Critical Appraisal tools. The quality of reporting will be determined with the Strengthening the Reporting of OBservational studies in Epidemiology. The data extraction will include study characteristics as well as sociodemographic, balance and mobility, sensory and neuromuscular, psychological, medical, medication and environmental factors. The results will be presented via figures, summary tables, meta-analysis (when possible) and narrative summaries.

ETHICS AND DISSEMINATION

No ethics approval will be required. Findings will be disseminated through publication and media.

PROSPERO REGISTRATION NUMBER

CRD42019118888; Pre-results.

摘要

介绍

经常(即每年>1 次)跌倒的老年人有发生功能下降和死亡的风险。由于方法学上的限制,如回忆偏倚,社区居住的老年人反复跌倒的关键危险因素尚未得到很好的确定。更好地了解反复跌倒的危险因素将有助于完善二级跌倒预防策略的临床实践指南。本系统评价的主要目的是在社区居住的老年人的前瞻性研究中检查反复跌倒的危险因素。

方法和分析

我们于 2019 年 4 月 25 日在 MEDLINE、EMBASE、PsycINFO 和 CINAHL 数据库以及灰色文献中进行了全面的文献检索。我们将围绕以下主题使用 MeSH 和关键词搜索术语:跌倒、复发、跌倒风险、衰老和前瞻性研究。将纳入每月监测 12 个月跌倒情况的前瞻性研究,以调查老年人反复跌倒的危险因素。一名作者将完成搜索。两名作者将去除重复项,并根据纳入标准筛选标题和摘要以确定其潜在纳入性。两名作者将筛选全文并使用试点提取表提取数据。将使用 Joanna Briggs 研究所流行率关键评估工具评估纳入研究的偏倚风险。使用加强观察性研究的报告标准(Strengthening the Reporting of OBservational studies in Epidemiology)来确定报告质量。数据提取将包括研究特征以及社会人口统计学、平衡和移动性、感觉和神经肌肉、心理、医学、药物和环境因素。结果将通过图表、总结表、(如有可能)荟萃分析和叙述性摘要呈现。

伦理和传播

不需要伦理批准。研究结果将通过发表和媒体传播。

PROSPERO 注册号:CRD42019118888;预结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f87/7223009/baa9eb7f0ff3/bmjopen-2019-033602f01.jpg

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