Jain Shruti, Guleria Kiran, Suneja Amita, Vaid Neelam B, Ahuja Sharmila
Department of Obstetrics and Gynaecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
Department of Obstetrics and Gynaecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
Int J Gynaecol Obstet. 2016 Mar;132(3):332-6. doi: 10.1016/j.ijgo.2015.08.005. Epub 2015 Dec 2.
To evaluate the prognostic value of the Sequential Organ Failure Assessment (SOFA) score among obstetric patients admitted to the intensive care unit (ICU).
A prospective study was conducted among 90 consecutive obstetric patients who were admitted to the ICU of Guru Teg Bahadur Hospital, Delhi, India, between October 6, 2010, and December 25, 2011. Maximum SOFA score was calculated for each of the six organ systems. Receiver operating characteristic curves were used to determine critical cutoff values for total, maximum total, and mean total SOFA scores at various time points.
Total SOFA score at admission displayed an area under the curve (AUC) of 0.949, a cutoff value of at least 8.5, sensitivity of 86.7%, and specificity of 90.0%. Maximum total SOFA score had an AUC of 0.980, a cutoff value of at least 10.0, sensitivity of 96.7%, and specificity of 90.0%. Mean total SOFA score had an AUC of 0.997, a cutoff value of at least 9.0, sensitivity of 96.7%, and specificity of 96.7%.
In terms of discriminatory power for predicting mortality among obstetric patients admitted to the ICU, total SOFA score at admission was the most relevant, simple, and accurate measure.
评估序贯器官衰竭评估(SOFA)评分对入住重症监护病房(ICU)的产科患者的预后价值。
对2010年10月6日至2011年12月25日期间连续入住印度德里古鲁·特格·巴哈杜尔医院ICU的90例产科患者进行了一项前瞻性研究。计算六个器官系统中每个系统的最高SOFA评分。采用受试者工作特征曲线来确定不同时间点总SOFA评分、最高总SOFA评分和平均总SOFA评分的临界截断值。
入院时总SOFA评分的曲线下面积(AUC)为0.949,截断值至少为8.5,灵敏度为86.7%,特异性为90.0%。最高总SOFA评分的AUC为0.980,截断值至少为10.0,灵敏度为96.7%,特异性为90.0%。平均总SOFA评分的AUC为0.997,截断值至少为9.0,灵敏度为96.7%,特异性为96.7%。
就预测入住ICU的产科患者死亡率的鉴别能力而言,入院时的总SOFA评分是最相关、简单且准确的指标。