连接数与核小体
Linking numbers and nucleosomes.
作者信息
Crick F H
出版信息
Proc Natl Acad Sci U S A. 1976 Aug;73(8):2639-43. doi: 10.1073/pnas.73.8.2639.
Abstract
In considering supercoils formed by closed double-stranded molecules of DNA certain mathematical concepts, such as the linking number and the twist, are needed. The meaning of these for a closed ribbon is explained and also that of the writhing number of a closed curve. Some simple examples are given, some of which may be relevant to the structure of chromatin.
摘要
在考虑由DNA的闭合双链分子形成的超螺旋时，需要某些数学概念，如连环数和扭转数。文中解释了这些概念对于闭合带状物的意义，以及闭合曲线的缠绕数的意义。还给出了一些简单的例子，其中一些可能与染色质的结构有关。
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