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Epilepsy in 2015: Classic antiepileptic drugs under fire, and new options emerge.

作者信息

Elger Christian E

机构信息

Department of Epileptology, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.

出版信息

Nat Rev Neurol. 2016 Feb;12(2):72-4. doi: 10.1038/nrneurol.2016.1. Epub 2016 Jan 22.

DOI:10.1038/nrneurol.2016.1

PMID:26794652

Abstract

摘要

相似文献

Epilepsy in 2015: Classic antiepileptic drugs under fire, and new options emerge.

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Current strategies in the medical management of epilepsy.

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引用本文的文献

Anti-high mobility group box protein 1 monoclonal antibody downregulating P-glycoprotein as novel epilepsy therapeutics.

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Involvement of nNOS, and α1, α2, β1, and β2 Subunits of Soluble Guanylyl Cyclase Genes Expression in Anticonvulsant Effect of Sumatriptan on Pentylenetetrazole-Induced Seizure in Mice.

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本文引用的文献

Zinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1.

Nat Commun. 2015 Oct 26;6:8688. doi: 10.1038/ncomms9688.

Mind the gap: Multiple events and lengthy delays before presentation with a "first seizure".

Epilepsia. 2015 Oct;56(10):1534-41. doi: 10.1111/epi.13127. Epub 2015 Aug 31.

Perampanel for tonic-clonic seizures in idiopathic generalized epilepsy A randomized trial.

Neurology. 2015 Sep 15;85(11):950-7. doi: 10.1212/WNL.0000000000001930.

Dose-dependent teratogenicity of valproate in mono- and polytherapy: an observational study.

Neurology. 2015 Sep 8;85(10):866-72. doi: 10.1212/WNL.0000000000001772. Epub 2015 Jun 17.

IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study.

Neurology. 2015 Jan 27;84(4):382-90. doi: 10.1212/WNL.0000000000001182. Epub 2014 Dec 24.

Treatment for epilepsy in pregnancy: neurodevelopmental outcomes in the child.

Cochrane Database Syst Rev. 2014 Oct 30;2014(10):CD010236. doi: 10.1002/14651858.CD010236.pub2.

Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers.

J Neurol Neurosurg Psychiatry. 2014 Sep;85(9):1029-34. doi: 10.1136/jnnp-2013-306318. Epub 2014 Jan 20.

Fetal antiepileptic drug exposure and cognitive outcomes at age 6 years (NEAD study): a prospective observational study.

Lancet Neurol. 2013 Mar;12(3):244-52. doi: 10.1016/S1474-4422(12)70323-X. Epub 2013 Jan 23.

The global burden and stigma of epilepsy.

Epilepsy Behav. 2008 May;12(4):540-6. doi: 10.1016/j.yebeh.2007.12.019. Epub 2008 Feb 14.

The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial.

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Epilepsy in 2015: Classic antiepileptic drugs under fire, and new options emerge.

作者信息

Elger Christian E

机构信息

Department of Epileptology, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.

出版信息

Nat Rev Neurol. 2016 Feb;12(2):72-4. doi: 10.1038/nrneurol.2016.1. Epub 2016 Jan 22.

DOI:10.1038/nrneurol.2016.1

PMID:26794652

Abstract

摘要

相似文献

Epilepsy in 2015: Classic antiepileptic drugs under fire, and new options emerge.

Nat Rev Neurol. 2016 Feb;12(2):72-4. doi: 10.1038/nrneurol.2016.1. Epub 2016 Jan 22.

Current strategies in the medical management of epilepsy.

J S C Med Assoc. 1992 May;88(5):221-9.

Some additional points on the obstetric perspective of epilepsy.

Am J Obstet Gynecol. 2004 Dec;191(6):2174; author reply 2175. doi: 10.1016/j.ajog.2004.06.116.

[Epilepsy in pregnancy].

Cesk Gynekol. 1993 Oct;58(5):249-54.

Safety of antiepileptic drugs during pregnancy.

Expert Opin Drug Saf. 2005 Sep;4(5):869-77. doi: 10.1517/14740338.4.5.869.

Antiepileptic drugs.

N Engl J Med. 1996 Jan 18;334(3):168-75. doi: 10.1056/NEJM199601183340308.

[Side effects of new antiepileptic drugs in children, pregnant women and elderly patients].

Lik Sprava. 2006 Jan-Sep(1-2):44-51.

Birth defects and epilepsy medication.

Expert Rev Neurother. 2006 Jun;6(6):833-45. doi: 10.1586/14737175.6.6.833.

The influence of antiepileptic drugs on minor anomalies in the offspring of epileptic parents.

Prog Clin Biol Res. 1985;163C:57-60.

The Australian Register of antiepileptic drugs in pregnancy: changes over time in the epileptic population.

J Clin Neurosci. 2014 Sep;21(9):1478-82. doi: 10.1016/j.jocn.2013.11.049. Epub 2014 Jun 10.

引用本文的文献

Anti-high mobility group box protein 1 monoclonal antibody downregulating P-glycoprotein as novel epilepsy therapeutics.

Egypt J Neurol Psychiatr Neurosurg. 2022;58(1):121. doi: 10.1186/s41983-022-00557-8. Epub 2022 Oct 22.

Involvement of nNOS, and α1, α2, β1, and β2 Subunits of Soluble Guanylyl Cyclase Genes Expression in Anticonvulsant Effect of Sumatriptan on Pentylenetetrazole-Induced Seizure in Mice.

Iran J Pharm Res. 2020 Fall;19(4):181-192. doi: 10.22037/ijpr.2020.112594.13844.

The ATP-Gated P2X7 Receptor As a Target for the Treatment of Drug-Resistant Epilepsy.

Front Neurosci. 2017 Feb 2;11:21. doi: 10.3389/fnins.2017.00021. eCollection 2017.

本文引用的文献

Zinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1.

Nat Commun. 2015 Oct 26;6:8688. doi: 10.1038/ncomms9688.

Mind the gap: Multiple events and lengthy delays before presentation with a "first seizure".

Epilepsia. 2015 Oct;56(10):1534-41. doi: 10.1111/epi.13127. Epub 2015 Aug 31.

Perampanel for tonic-clonic seizures in idiopathic generalized epilepsy A randomized trial.

Neurology. 2015 Sep 15;85(11):950-7. doi: 10.1212/WNL.0000000000001930.

Dose-dependent teratogenicity of valproate in mono- and polytherapy: an observational study.

Neurology. 2015 Sep 8;85(10):866-72. doi: 10.1212/WNL.0000000000001772. Epub 2015 Jun 17.

IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study.

Neurology. 2015 Jan 27;84(4):382-90. doi: 10.1212/WNL.0000000000001182. Epub 2014 Dec 24.

Treatment for epilepsy in pregnancy: neurodevelopmental outcomes in the child.

Cochrane Database Syst Rev. 2014 Oct 30;2014(10):CD010236. doi: 10.1002/14651858.CD010236.pub2.

Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers.

J Neurol Neurosurg Psychiatry. 2014 Sep;85(9):1029-34. doi: 10.1136/jnnp-2013-306318. Epub 2014 Jan 20.

Fetal antiepileptic drug exposure and cognitive outcomes at age 6 years (NEAD study): a prospective observational study.

Lancet Neurol. 2013 Mar;12(3):244-52. doi: 10.1016/S1474-4422(12)70323-X. Epub 2013 Jan 23.

The global burden and stigma of epilepsy.

Epilepsy Behav. 2008 May;12(4):540-6. doi: 10.1016/j.yebeh.2007.12.019. Epub 2008 Feb 14.

The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial.

Lancet. 2007 Mar 24;369(9566):1016-26. doi: 10.1016/S0140-6736(07)60461-9.