Miravitlles Marc, Vogelmeier Claus, Roche Nicolas, Halpin David, Cardoso João, Chuchalin Alexander G, Kankaanranta Hannu, Sandström Thomas, Śliwiński Paweł, Zatloukal Jaromir, Blasi Francesco
Pneumology Dept, University Hospital Vall d'Hebron, Ciber de Enfermedades Respiratorias (CIBERES), Barcelona, Spain
Dept of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Philipps-University Marburg, German Center for Lung Research (DZL), Marburg, Germany.
Eur Respir J. 2016 Feb;47(2):625-37. doi: 10.1183/13993003.01170-2015. Epub 2016 Jan 21.
The quality of care can be improved by the development and implementation of evidence-based treatment guidelines. Different national guidelines for chronic obstructive pulmonary disease (COPD) exist in Europe and relevant differences may exist among them.This was an evaluation of COPD treatment guidelines published in Europe and Russia in the past 7 years. Each guideline was reviewed in detail and information about the most important aspects of patient diagnosis, risk stratification and pharmacotherapy was extracted following a standardised process. Guidelines were available from the Czech Republic, England and Wales, Finland, France, Germany, Italy, Poland, Portugal, Russia, Spain and Sweden. The treatment goals, criteria for COPD diagnosis, consideration of comorbidities in treatment selection and support for use of long-acting bronchodilators, were similar across treatment guidelines. There were differences in measures used for stratification of disease severity, consideration of patient phenotypes, criteria for the use of inhaled corticosteroids and recommendations for other medications (e.g. theophylline and mucolytics) in addition to bronchodilators.There is generally good agreement on treatment goals, criteria for diagnosis of COPD and use of long-acting bronchodilators as the cornerstone of treatment among guidelines for COPD management in Europe and Russia. However, there are differences in the definitions of patient subgroups and other recommended treatments.
通过制定和实施循证治疗指南,可以提高医疗质量。欧洲存在不同的慢性阻塞性肺疾病(COPD)国家指南,它们之间可能存在相关差异。这是一项对过去7年在欧洲和俄罗斯发表的COPD治疗指南的评估。对每个指南进行了详细审查,并按照标准化流程提取了有关患者诊断、风险分层和药物治疗最重要方面的信息。指南来自捷克共和国、英格兰和威尔士、芬兰、法国、德国、意大利、波兰、葡萄牙、俄罗斯、西班牙和瑞典。各治疗指南在治疗目标、COPD诊断标准、治疗选择中对合并症的考虑以及对使用长效支气管扩张剂的支持方面相似。在疾病严重程度分层所采用的措施、对患者表型的考虑、吸入性糖皮质激素的使用标准以及除支气管扩张剂外其他药物(如茶碱和黏液溶解剂)的推荐方面存在差异。在欧洲和俄罗斯的COPD管理指南中,对于治疗目标、COPD诊断标准以及使用长效支气管扩张剂作为治疗基石方面,总体上有很好的共识。然而,在患者亚组的定义和其他推荐治疗方面存在差异。