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女性压力性尿失禁治疗后膀胱储尿期症状的变化

Change in urinary storage symptoms following treatment for female stress urinary incontinence.

作者信息

Padmanabhan Priya, Panfili Zachary, Parker William, Gomelsky Alexander

机构信息

Department of Urology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS, 66160, USA.

Department of Urology, Louisiana State University Health-Shreveport, 1501 Kings Highway, Shreveport, LA, 71130, USA.

出版信息

Int Urogynecol J. 2016 Aug;27(8):1169-74. doi: 10.1007/s00192-016-2951-6. Epub 2016 Jan 21.

Abstract

INTRODUCTION AND HYPOTHESIS

Sling surgery is common for stress urinary incontinence (SUI). Yet many women have stress-predominant mixed urinary incontinence (MUI). The change in urgency/urge urinary incontinence (U/UUI) following treatment is not well documented. Our aim was to assess changes in U/UUI in women undergoing a sling placement for MUI and correlate this with improvement in quality of life (QOL).

METHODS

This was a retrospective review of women treated for SUI with either an autologous rectus fascia pubovaginal sling (AF-PVS) or synthetic retropubic midurethral sling (MUS). Validated questionnaires-Urogenital Distress Inventory (UDI-6), Incontinence Impact Questionnaire-Short Form (IIQ-7), and visual analog scale (VAS) were obtained pre- and postoperatively. The independent association between change in storage symptoms and subjective cure-as defined by improved overall score on UDI-6, VAS score ≥ 7, or both -were assessed using multivariate logistic regression.

RESULTS

Nine hundred and twenty-seven women were identified for inclusion; 718 (77.5 %) had preoperative MUI, of whom 487 (67.8 %) received an MUS and 231 (32.2 %) an AF-PVS. Similar objective cure rates were noted following MUS vs. AF-PVS (78.2 % vs. 71.9 %, p = 0.315). Subjectively, women treated with MUS experienced greater improvement in U/UUI (72.8 % vs. 57.6 %, p = <0.001) than AF-PVS. Multivariate analysis showed MUS patients were more than twice as likely to show subjective improvement in UDI-6 and VAS scores than the AF-PVS cohort. Postoperatively, validated questionnaires were significantly associated with storage symptom outcome.

CONCLUSIONS

Patients with U/UUI experience significant symptom improvement following treatment for MUI. QoL assessment following surgery is directly correlated with improvement in U/UUI.

摘要

引言与假设

吊带手术常用于治疗压力性尿失禁(SUI)。然而,许多女性患有以压力性为主的混合性尿失禁(MUI)。治疗后尿急/急迫性尿失禁(U/UUI)的变化情况尚无充分记录。我们的目的是评估接受MUI吊带置入术的女性U/UUI的变化,并将其与生活质量(QOL)的改善情况相关联。

方法

这是一项对接受自体腹直肌筋膜耻骨后阴道吊带术(AF-PVS)或合成耻骨后中段尿道吊带术(MUS)治疗SUI的女性进行的回顾性研究。术前和术后均获取了经过验证的问卷——泌尿生殖系统困扰量表(UDI-6)、尿失禁影响问卷简表(IIQ-7)和视觉模拟量表(VAS)。使用多因素逻辑回归分析评估储尿期症状变化与主观治愈之间的独立关联,主观治愈定义为UDI-6总分改善、VAS评分≥7分或两者均满足。

结果

确定纳入927名女性;718名(77.5%)术前患有MUI,其中487名(67.8%)接受了MUS,231名(32.2%)接受了AF-PVS。MUS与AF-PVS术后的客观治愈率相似(分别为78.2%和71.9%,p = 0.315)。主观上,接受MUS治疗的女性在U/UUI方面的改善程度(72.8%对57.6%,p < 0.001)高于AF-PVS。多因素分析显示,MUS患者在UDI-6和VAS评分上主观改善的可能性是AF-PVS队列的两倍多。术后,经过验证的数据问卷与储尿期症状结果显著相关。

结论

U/UUI患者在接受MUI治疗后症状有显著改善。术后的生活质量评估与U/UUI的改善直接相关。

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