Wagenlehner Florian, Tandogdu Zafer, Bartoletti Riccardo, Cai Tommaso, Cek Mete, Kulchavenya Ekaterina, Köves Béla, Naber Kurt, Perepanova Tamara, Tenke Peter, Wullt Björn, Bogenhard Florian, Johansen Truls Erik Bjerklund
Department of Urology, Paediatric Urology and Andrology, Justus-Liebig-University, D-35392 Giessen, Germany.
Northern Institute for Cancer Research, Newcastle University, Newcastle Upon Tyne NE2 4HH, UK.
Pathogens. 2016 Jan 19;5(1):10. doi: 10.3390/pathogens5010010.
The Global Prevalence of Infections in Urology (GPIU) study is a worldwide-performed point prevalence study intended to create surveillance data on antibiotic resistance, type of urogenital infections, risk factors and data on antibiotic consumption, specifically in patients at urological departments with healthcare-associated urogenital infections (HAUTI). Investigators registered data through a web-based application (http://gpiu.esiu.org/). Data collection includes the practice and characteristics of the hospital and urology ward. On a certain day in November, each year, all urological patients present in the urological department at 8:00 a.m. are screened for HAUTI encompassing their full hospital course from admission to discharge. Apart from the GPIU main study, several side studies are taking place, dealing with transurethral resection of the prostate, prostate biopsy, as well as urosepsis. The GPIU study has been annually performed since 2003. Eight-hundred fifty-six urology units from 70 countries have participated so far, including 27,542 patients. A proxy for antibiotic consumption is reflected by the application rates used for antibiotic prophylaxis for urological interventions. Resistance rates of most uropathogens against antibiotics were high, especially with a note of multidrug resistance. The severity of HAUTI is also increasing, 25% being urosepsis in recent years.
全球泌尿外科感染患病率（GPIU）研究是一项在全球范围内开展的现患率研究，旨在创建关于抗生素耐药性、泌尿生殖系统感染类型、危险因素以及抗生素消费数据的监测数据，特别是针对患有医疗保健相关泌尿生殖系统感染（HAUTI）的泌尿外科患者。研究人员通过一个基于网络的应用程序（http://gpiu.esiu.org/）登记数据。数据收集包括医院和泌尿外科病房的业务情况及特征。在每年11月的某一天，对上午8点时在泌尿外科就诊的所有泌尿外科患者进行HAUTI筛查，涵盖从入院到出院的整个住院过程。除了GPIU主要研究外，还开展了几项附带研究，涉及前列腺经尿道切除术、前列腺活检以及尿脓毒症。GPIU研究自2003年起每年进行。迄今为止，来自70个国家的856个泌尿外科单位参与其中，包括27542名患者。用于泌尿外科干预抗生素预防的应用率反映了抗生素消费情况。大多数尿路病原体对抗生素的耐药率很高，特别是存在多重耐药情况。HAUTI的严重程度也在增加，近年来25%的病例为尿脓毒症。
