Diz Juliano Bergamaschine Mata, Leopoldino Amanda Aparecida Oliveira, Moreira Bruno de Souza, Henschke Nicholas, Dias Rosangela Correa, Pereira Leani Souza Máximo, Oliveira Vinicius Cunha
Postgraduate Program in Rehabilitation Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
The George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
Geriatr Gerontol Int. 2017 Jan;17(1):5-16. doi: 10.1111/ggi.12720. Epub 2016 Jan 22.
Sarcopenia is the age-related loss of muscle mass and function that evolves into disability, loss of independence and death. In Brazil the number of older people is rapidly growing, resulting in an increased prevalence of chronic conditions associated with old age. As prevalence estimates provide essential information to policymakers when developing healthcare strategies, this systematic review and meta-analysis aimed to estimate the prevalence of sarcopenia in older Brazilians.
Electronic database searches and hand-searching in relevant journals and reference lists were carried out without language restriction. Studies that reported the prevalence of sarcopenia in Brazilians aged 60 years or older were considered for inclusion. Sarcopenia was defined as low muscle mass, low muscle function or low muscle mass and function. Meta-analysis was carried out using a random-effects model.
A total of 31 studies were included pooling 9416 participants. The overall prevalence of sarcopenia in older Brazilians was 17.0% (95% CI 13.0-22.0). Sensitivity analysis showed rates of 20.0% (95% CI 11.0-32.0) in women and 12.0% (95% CI 9.0-16.0) in men. Prevalence was 16.0% (95% CI 12.0-23.0) based on low muscle mass and function; and 17.0% (95% CI 9.0-31.0) based only on low muscle mass. The difference between these two criteria was not significant (P = 0.96).
Sarcopenia is an emerging public health issue in Brazil. Attention should be paid to changes in prevalence rates over the next years because of the increase in the older population. Geriatr Gerontol Int 2017; 17: 5-16.
肌肉减少症是与年龄相关的肌肉质量和功能丧失，会发展为残疾、失去独立能力甚至死亡。在巴西，老年人数量迅速增长，导致与老年相关的慢性病患病率上升。由于患病率估计为政策制定者制定医疗保健策略提供了重要信息，因此本系统评价和荟萃分析旨在估计巴西老年人中肌肉减少症的患病率。
进行电子数据库检索，并对相关期刊和参考文献列表进行手工检索，无语言限制。纳入报告了60岁及以上巴西人肌肉减少症患病率的研究。肌肉减少症定义为低肌肉量、低肌肉功能或低肌肉量和功能。使用随机效应模型进行荟萃分析。
共纳入31项研究，汇总了9416名参与者。巴西老年人中肌肉减少症的总体患病率为17.0%（95%可信区间13.0 - 22.0）。敏感性分析显示，女性患病率为20.0%（95%可信区间11.0 - 32.0），男性为12.0%（95%可信区间9.0 - 16.0）。基于低肌肉量和功能的患病率为16.0%（95%可信区间12.0 - 23.0）；仅基于低肌肉量的患病率为17.0%（95%可信区间9.0 - 31.0）。这两个标准之间的差异不显著（P = 0.96）。
肌肉减少症在巴西是一个新出现的公共卫生问题。由于老年人口增加，未来几年应关注患病率的变化。《老年医学与老年病学国际杂志》2017年；17：5 - 16。
