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高血压预防试验中的治疗。高血压预防试验研究组。

Treatment in the Hypertension Prevention Trial. Hypertension Prevention Trial Research Group.

作者信息

Jeffery R W, Tonascia S, Bjornson-Benson W, Schlundt D G, Sugars C

机构信息

Johns Hopkins School of Hygiene and Public Health, Department of Epidemiology, Baltimore, Md 21205.

出版信息

Control Clin Trials. 1989 Sep;10(3 Suppl):65S-83S. doi: 10.1016/0197-2456(89)90043-3.

DOI:10.1016/0197-2456(89)90043-3
PMID:2680274
Abstract

The Hypertension Prevention Trial (HPT) was a randomized, controlled, multicenter (four clinics, four resource centers) trial designed to test the feasibility of achieving and sustaining dietary changes in the intake of calories, sodium, and potassium and to assess the effect of those changes on blood pressure in a normotensive population. The trial involved 841 men and women (plus a test cohort of 78) who, at the first baseline (BL) examination were in the age range of 25-49 years and had diastolic blood pressure (DBP) greater than or equal to 76 but less than 100 mm Hg (average of two readings), and at the examination prior to randomization (BL 2) had DBP greater than or equal to 78 but less than 90 mm Hg (also averaged). Participants were randomly assigned to a control treatment group (no dietary counseling) or to one of four dietary treatment groups involving counseling designed to reduce calorie intake, reduce sodium intake, reduce sodium and calorie intake, and reduce sodium and increase potassium intake. This chapter describes the counseling methods employed to help participants achieve the desired dietary changes. Counseling was provided to groups by trained interventionists and included instruction in food selection, food preparation, and behavior management skills. Counseling groups met weekly for the first 10 weeks of the trial, twice the following month, and bimonthly thereafter. Techniques used in the counseling program included group discussions, instructions for dietary record keeping, goal setting, individual diet analysis for each participant, cooking demonstrations, and taste testing of new foods.

摘要

高血压预防试验(HPT)是一项随机、对照、多中心(四个诊所、四个资源中心)试验,旨在测试在正常血压人群中实现并维持热量、钠和钾摄入量的饮食变化的可行性,并评估这些变化对血压的影响。该试验涉及841名男性和女性(外加一个78人的测试队列),他们在第一次基线(BL)检查时年龄在25至49岁之间,舒张压(DBP)大于或等于76但小于100毫米汞柱(两次读数的平均值),在随机分组前的检查(BL 2)时DBP大于或等于78但小于90毫米汞柱(也是平均值)。参与者被随机分配到一个对照治疗组(无饮食咨询)或四个饮食治疗组之一,这些组涉及旨在减少热量摄入、减少钠摄入、减少钠和热量摄入以及减少钠并增加钾摄入的咨询。本章描述了为帮助参与者实现所需饮食变化而采用的咨询方法。由经过培训的干预人员向各小组提供咨询,内容包括食物选择、食物制备和行为管理技能方面的指导。咨询小组在试验的前10周每周开会,接下来的一个月每周开两次会,此后每两个月开一次会。咨询项目中使用的技术包括小组讨论、饮食记录保存指导、目标设定、对每个参与者的个人饮食分析、烹饪示范以及新食物的口味测试。

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Treatment in the Hypertension Prevention Trial. Hypertension Prevention Trial Research Group.高血压预防试验中的治疗。高血压预防试验研究组。
Control Clin Trials. 1989 Sep;10(3 Suppl):65S-83S. doi: 10.1016/0197-2456(89)90043-3.
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Design, methods, and rationale in the Hypertension Prevention Trial. Hypertension Prevention Trial Research Group.高血压预防试验的设计、方法及理论依据。高血压预防试验研究组
Control Clin Trials. 1989 Sep;10(3 Suppl):1S-29S. doi: 10.1016/0197-2456(89)90040-8.
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Quality assurance and monitoring in the Hypertension Prevention Trial. Hypertension Prevention Trial Research Group.高血压预防试验中的质量保证与监测。高血压预防试验研究组。
Control Clin Trials. 1989 Sep;10(3 Suppl):84S-94S. doi: 10.1016/0197-2456(89)90044-5.
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Recruitment in the Hypertension Prevention trial. Hypertension Prevention Trial Research Group.高血压预防试验中的招募。高血压预防试验研究组。
Control Clin Trials. 1989 Sep;10(3 Suppl):30S-39S. doi: 10.1016/0197-2456(89)90041-x.
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Baseline characteristics in the Hypertension Prevention Trial. Hypertension Prevention Trial Research Group.高血压预防试验的基线特征。高血压预防试验研究组
Control Clin Trials. 1989 Sep;10(3 Suppl):40S-64S. doi: 10.1016/0197-2456(89)90042-1.
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Hypertension Prevention Trial (HPT): food pattern changes resulting from intervention on sodium, potassium, and energy intake. Hypertension Prevention Trial Research Group.高血压预防试验(HPT):钠、钾和能量摄入干预导致的饮食模式变化。高血压预防试验研究组
J Am Diet Assoc. 1990 Jan;90(1):69-76.
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The Hypertension Prevention Trial: three-year effects of dietary changes on blood pressure. Hypertension Prevention Trial Research Group.高血压预防试验:饮食改变对血压的三年影响。高血压预防试验研究组
Arch Intern Med. 1990 Jan;150(1):153-62.
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The PREMIER intervention helps participants follow the Dietary Approaches to Stop Hypertension dietary pattern and the current Dietary Reference Intakes recommendations.“总理干预措施”帮助参与者遵循“终止高血压膳食方法”饮食模式以及当前的膳食参考摄入量建议。
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Hypertension prevention trial: do 24-h food records capture usual eating behavior in a dietary change study?高血压预防试验:在一项饮食改变研究中,24小时食物记录能否反映通常的饮食行为?
Am J Clin Nutr. 1990 Feb;51(2):253-7. doi: 10.1093/ajcn/51.2.253.
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Does pragmatically structured outpatient dietary counselling reduce sodium intake in hypertensive patients? Study protocol for a randomized controlled trial.实用结构化门诊饮食咨询能否降低高血压患者的钠摄入量?一项随机对照试验的研究方案。
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