Varan Aiden K, Harriman Kathleen H, Winter Kathleen, Thun Melissa D, McDonald Eric C
CDC/CSTE Applied Epidemiology Fellowship, Atlanta, Georgia; County of San Diego Health and Human Services Agency, San Diego, California; Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, San Diego, California.
California Department of Public Health, Richmond, California.
J Adolesc Health. 2016 Feb;58(2):241-4. doi: 10.1016/j.jadohealth.2015.10.012.
During recent pertussis epidemics, adolescents have experienced a large burden of disease. We assessed the impact of pertussis among San Diego adolescents and their households.
Parents of pertussis patients aged 13-17 years were surveyed about health care utilization, missed work and school, and other factors. Costs of medical visits, medication use, and lost wages were estimated.
The parents of 53 (of 108 [49%]) eligible 2013 pertussis patients were interviewed; 51 (96%) of these patients previously received tetanus, diphtheria, and acellular pertussis vaccine. Medical visits included primary care (81%), urgent care (11%), and emergency department (9%); all patients received antibiotics. Forty-seven households (89%) received a post-exposure prophylaxis recommendation, and five (9%) reported ≥1 unpaid parental leave day. Thirty-eight patients (72%) missed ≥1 school day (mean = 5.4 days). Societal costs were estimated at $315.15 per household and $236,047.35 in San Diego during 2013-2014.
Even among vaccinated adolescents, pertussis can result in considerable societal costs.
在近期的百日咳流行期间，青少年承受了巨大的疾病负担。我们评估了百日咳对圣地亚哥青少年及其家庭的影响。
对13至17岁百日咳患者的父母就医疗保健利用情况、误工和缺课情况以及其他因素进行了调查。估算了就诊费用、药物使用费用和工资损失。
对2013年符合条件的108名百日咳患者中的53名（49%）患者的父母进行了访谈；这些患者中有51名（96%）之前接种过破伤风、白喉和无细胞百日咳疫苗。就诊包括初级保健（81%）、紧急护理（11%）和急诊科（9%）；所有患者均接受了抗生素治疗。47户家庭（89%）收到了暴露后预防建议，5户家庭（9%）报告有≥1天的无薪育儿假。38名患者（72%）缺课≥1天（平均 = 5.4天）。2013 - 2014年期间，圣地亚哥每户家庭的社会成本估计为315.15美元，总计236,047.35美元。
即使在接种过疫苗的青少年中，百日咳也会导致相当大的社会成本。
