百日咳流行病学的变化：旧貌换新颜。

Changing pertussis epidemiology: everything old is new again.

机构信息

Centers for Disease Control and Prevention, Atlanta, Georgia.

出版信息

J Infect Dis. 2014 Apr 1;209(7):978-81. doi: 10.1093/infdis/jiu001.

Abstract

Before vaccination, pertussis was a universal disease of early childhood. Although apparent control of the disease in the United States and other countries was achieved through vaccination, pertussis is resurgent. Though acellular vaccines have been in use for 20 years, new data are emerging on their effectiveness and durability of protection and the contribution of these characteristics to the resurgence of pertussis.

摘要

在疫苗接种之前，百日咳是一种普遍发生于幼儿期的疾病。尽管通过疫苗接种在美国和其他国家实现了对该病的明显控制，但百日咳仍在卷土重来。虽然无细胞疫苗已经使用了 20 年，但关于其有效性和保护持久性的新数据以及这些特性对百日咳卷土重来的影响正在不断涌现。