Villet R, Gadonneix P, Khebichat N, Scali P, Van der Akker M
Chirurgie. 1989;115(3):178-83; discussion 183-4.
This is a retrospective study including 102 cases records of female patients presenting with epithelial carcinoma of the ovary. Survival, as in the other series, depended upon the stage of the cancer at the time of diagnosis, mean survival rates being 77.1, 57.7, 26.6 and 19.3 for stages I, II, III and IV respectively. However, most of all, survival was related to the quantity of remanent tumoral tissue following the initial laparotomy. The 5-year survival rates were 84%, 42% and 10% when there was no residual tumor, when the latter measured less than 2 cm, and more than 2 cm, respectively. In contradistinction to what is generally found in such studies, the diagnosis here was established at earlier stages, since 53% of the cases of interest were female patients with stage I or II carcinoma. The chief argument, therefore, is based on the methods of early diagnosis and, judging from what is generally admitted in literature, on the place of extended surgery.
这是一项回顾性研究,纳入了102例卵巢上皮癌女性患者的病例记录。与其他系列研究一样,生存率取决于诊断时癌症的分期,I、II、III和IV期的平均生存率分别为77.1%、57.7%、26.6%和19.3%。然而,最重要的是,生存率与初次剖腹手术后残留肿瘤组织的数量有关。无残留肿瘤、残留肿瘤小于2 cm和大于2 cm时的5年生存率分别为84%、42%和10%。与这类研究中通常发现的情况不同,这里的诊断在更早阶段确立,因为感兴趣的病例中有53%是I期或II期癌的女性患者。因此,主要论点基于早期诊断方法,并且从文献中普遍认可的情况来看,基于扩大手术的地位。