Schwendemann G, Schulz M
Neurologische Klinik der Universitätsklinik Essen.
Fortschr Neurol Psychiatr. 1989 Oct;57(10):425-33. doi: 10.1055/s-2007-1001138.
Immunoneuropathies constitute but a small percentage of polyneuropathies, compared to metabolic or toxic neuropathies. However, refined techniques of immunochemistry and biopsy have increasingly improved the etiological characterisation of immunoneuropathies. This review deals with the present diagnostic tools for investigation of polyneuropathies in general and with special immunological means of diagnosis. After two short case reports from our department, the main groups of peripheral nerve diseases, in which immunologic pathomechanisms are postulated, are described regarding symptomatology, special diagnostics and therapy. These groups of diseases are listed with respect to scientific evidence of their immunologic etiology, ranging from acute and chronic Guillain-Barré-Syndrome to paraneoplastic and neuropathies in HIV infections. The conclusion gives a summary of general pathogenetic considerations in immunoneuropathies.
与代谢性或中毒性多发性神经病相比，免疫性神经病在多发性神经病中所占比例很小。然而，免疫化学和活检的精细技术日益改进了免疫性神经病的病因学特征描述。本综述讨论了一般用于研究多发性神经病的现有诊断工具以及特殊的免疫学诊断方法。在我们科室的两例简短病例报告之后，描述了假定存在免疫病理机制的主要周围神经疾病组，涉及症状学、特殊诊断和治疗。这些疾病组根据其免疫病因学的科学证据列出，范围从急性和慢性吉兰 - 巴雷综合征到副肿瘤性神经病和HIV感染中的神经病。结论部分总结了免疫性神经病的一般发病机制考量。
