对从0至5岁儿童急性腹泻中分离出的典型肠致病性大肠杆菌菌株致病性的研究。
Studies on the pathogenicity of classical enteropathogenic Escherichia coli strains isolated from acute diarrhoea among children 0-5 years of age.
作者信息
Ananthan S, Subramanian S, Thyagarajan S P, Jayakumar V, Udayashankar K, Elanchezhiyan M, Shanmugasundaram N
出版信息
Indian J Pathol Microbiol. 1989 Apr;32(2):92-100.
The mechanisms of pathogenicity in EPEC strains were studied in tissue culture. Escherichia coli was isolated as the predominant organism in the primary culture of 1293 (70.54%) diarrhoeal cases. 284 (90.44%) cases from the age group of 1-6 months showed Escherichia coli as the predominant organism. Classical Enteropathogenic Escherichia coli) were detected in 311 (24.05%) cases. Among EPEC isolates 277 (89.06%) did not produce either LT or ST 32(10.28%) produced LT or ST. 2 strains produced verotoxins belong to serotypes 0:86; K:61, 0:26; K:60, sero groups 0.86 :K:61, 0.142:K 86, 0.128:K 67, 0.126:K 71, 0125:K 70 0119:K69 showed localised adherence and serogroups 0111:K58-055:K59 showed both localised and diffused adherence to HeLa cells.
在组织培养中研究了肠致病性大肠杆菌（EPEC）菌株的致病机制。在1293例腹泻病例（70.54%）的原代培养物中，分离出大肠杆菌作为主要微生物。1 - 6个月龄组的284例病例（90.44%）显示大肠杆菌为主要微生物。在311例病例（24.05%）中检测到典型肠致病性大肠杆菌。在EPEC分离株中，277株（89.06%）既不产生LT也不产生ST，32株（10.28%）产生LT或ST。2株产生属于0:86；K:61、0:26；K:60血清型的志贺毒素，血清群0.86 :K:61、0.142:K 86、0.128:K 67、0.126:K 71、0125:K 70、0119:K69表现出局部黏附，血清群0111:K58 - 055:K59对HeLa细胞表现出局部和弥漫性黏附。
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