Ananthan S, Subramanian S, Thyagarajan S P, Jayakumar V, Udayashankar K, Elanchezhiyan M, Shanmugasundaram N
Indian J Pathol Microbiol. 1989 Apr;32(2):92-100.
The mechanisms of pathogenicity in EPEC strains were studied in tissue culture. Escherichia coli was isolated as the predominant organism in the primary culture of 1293 (70.54%) diarrhoeal cases. 284 (90.44%) cases from the age group of 1-6 months showed Escherichia coli as the predominant organism. Classical Enteropathogenic Escherichia coli) were detected in 311 (24.05%) cases. Among EPEC isolates 277 (89.06%) did not produce either LT or ST 32(10.28%) produced LT or ST. 2 strains produced verotoxins belong to serotypes 0:86; K:61, 0:26; K:60, sero groups 0.86 :K:61, 0.142:K 86, 0.128:K 67, 0.126:K 71, 0125:K 70 0119:K69 showed localised adherence and serogroups 0111:K58-055:K59 showed both localised and diffused adherence to HeLa cells.
在组织培养中研究了肠致病性大肠杆菌（EPEC）菌株的致病机制。在1293例腹泻病例（70.54%）的原代培养物中，分离出大肠杆菌作为主要微生物。1 - 6个月龄组的284例病例（90.44%）显示大肠杆菌为主要微生物。在311例病例（24.05%）中检测到典型肠致病性大肠杆菌。在EPEC分离株中，277株（89.06%）既不产生LT也不产生ST，32株（10.28%）产生LT或ST。2株产生属于0:86；K:61、0:26；K:60血清型的志贺毒素，血清群0.86 :K:61、0.142:K 86、0.128:K 67、0.126:K 71、0125:K 70、0119:K69表现出局部黏附，血清群0111:K58 - 055:K59对HeLa细胞表现出局部和弥漫性黏附。
