[尿素的生物化学、药理学与毒理学]

[Biochemistry, pharmacology and toxicology of urea].

作者信息

Raab W

机构信息

Allergieambulatorium, Wien.

出版信息

Hautarzt. 1989;40 Suppl 9:23-6.

PMID:2681074

Abstract

In modern dermatology urea has two areas of application: --Applied topically urea is a pharmacologically active substance. It is moisturizing, keratolytic (in high concentrations only), desquamating, antipruritic, and antimicrobial. --Urea supplements and increases the effectivity of glucocorticoids, anthralin (dithranol) and tretinion. Urea-glucocorticoid combinations deserve special attention.

摘要

在现代皮肤病学中，尿素有两个应用领域：——局部应用时，尿素是一种具有药理活性的物质。它具有保湿、角质溶解作用（仅在高浓度时）、去屑、止痒和抗菌作用。——尿素可补充并增强糖皮质激素、蒽林（地蒽酚）和维甲酸的疗效。尿素 - 糖皮质激素组合值得特别关注。