Marino G G
J Am Osteopath Assoc. 1989 Oct;89(10):1323-6, 1329.
Acute myelofibrosis is a rare hematologic disorder characterized by pancytopenia, normal erythrocyte morphology, extensive marrow fibrosis, and a rapidly fatal clinical course. The etiology of this disease is unknown, but the malignant cell may be of megakaryocytic lineage. Although allogeneic bone marrow transplantation may be effective in achieving complete hematologic remission, optimal management of this rare and often rapidly fatal disease remains to be defined.
急性骨髓纤维化是一种罕见的血液系统疾病，其特征为全血细胞减少、红细胞形态正常、广泛的骨髓纤维化以及快速致死的临床病程。该疾病的病因尚不清楚，但恶性细胞可能源自巨核细胞系。尽管异基因骨髓移植可能有效实现完全血液学缓解，但这种罕见且通常快速致死疾病的最佳治疗方案仍有待确定。
