Goldberg N S, Weiss S S
Department of Dermatology, New York Medical College.
J Am Acad Dermatol. 1989 Nov;21(5 Pt 2):1115-8. doi: 10.1016/s0190-9622(89)70309-1.
A case of pemphigus vulgaris with esophageal involvement is discussed and 10 other reported cases are reviewed. Esophageal involvement is a rare but serious occurrence. It is most readily diagnosed by endoscopy when dysphagia or odynophagia in a patient with pemphigus vulgaris or with a history of pemphigus vulgaris does not respond to appropriate adjustment of corticosteroid or other therapy. All patients with esophageal pemphigus vulgaris were middle-aged women. None had skin lesions at the time esophageal disease was diagnosed, and five patients appeared to be in complete remission, with neither skin nor oral lesions, when esophageal involvement was discovered.
本文讨论了一例累及食管的寻常型天疱疮病例，并回顾了其他10例已报道的病例。食管受累是一种罕见但严重的情况。当寻常型天疱疮患者或有寻常型天疱疮病史的患者出现吞咽困难或吞咽痛，且在适当调整皮质类固醇或其他治疗后无反应时，通过内镜检查最容易诊断。所有食管寻常型天疱疮患者均为中年女性。在诊断食管疾病时，无一例有皮肤病变，5例在发现食管受累时似乎处于完全缓解状态，既无皮肤病变也无口腔病变。
