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50岁以下年轻成年人髋部骨折的临床风险因素

Clinical Risk Factors for Hip Fracture in Young Adults Under 50 Years Old.

作者信息

Cheng Kenneth, Montgomery Sandy, Housley Sarah, Wheelwright Eugene

机构信息

Department of Orthopaedic Surgery, Glasgow Royal Infirmary, Glasgow, Scotland, UK.

, 7 Dalkeith Avenue, Dumbreck, Glasgow, UK.

出版信息

Eur J Trauma Emerg Surg. 2009 Feb;35(1):40-2. doi: 10.1007/s00068-008-7177-y. Epub 2008 Jul 22.

Abstract

BACKGROUND

Established risk factors for hip fracture exist for older individuals. Young adults (less than 50 years old) presenting with hip fractures have received little attention.

METHODS

The records of all adults, presenting over a 5-year period (1999-2004), to a large inner city teaching hospital, with a diagnosis of hip fracture, were reviewed. Of the 2,778 subjects, 196 involved people less than 65 years of age, limiting this to those less than 50 years old left 42 subjects [30 F/12 M, median (IQR) age 43 (37-47) years old]. Stepwise logistic regression analysis was performed to examine for clinical risk factors.

RESULTS

In this cohort regression analysis revealed a history of high impact trauma (β = 0.219, p = 0.002) and intravenous drug abuse (β = 0.206, p = 0.003) as predictors for risk of hip fracture.

CONCLUSIONS

Our data suggest that intravenous drug abusers under 50 are a particular group that we should be targeting for intervention strategies.

摘要

背景

老年人髋部骨折的既定风险因素已为人所知。年轻成年人(小于50岁)出现髋部骨折很少受到关注。

方法

回顾了一家大型市中心教学医院在5年期间(1999 - 2004年)所有诊断为髋部骨折的成年人记录。在2778名受试者中,196名年龄小于65岁,将范围限定在小于50岁的人群后剩下42名受试者[30名女性/12名男性,年龄中位数(四分位间距)为43(37 - 47)岁]。进行逐步逻辑回归分析以检查临床风险因素。

结果

在该队列中,回归分析显示高冲击力创伤史(β = 0.219,p = 0.002)和静脉药物滥用(β = 0.206,p = 0.003)是髋部骨折风险的预测因素。

结论

我们的数据表明,50岁以下的静脉药物滥用者是我们应针对干预策略的特定群体。

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