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不论创伤机制如何,年轻和中年股骨颈骨折患者都存在常见的骨质疏松症危险因素。

Risk factors for osteoporosis are common in young and middle-aged patients with femoral neck fractures regardless of trauma mechanism.

机构信息

Institute of Clinical Science, Intervention and Technology (CLINTEC), Department of Orthopaedics, Karolinska University Hospital, Sweden.

出版信息

Acta Orthop. 2013 Feb;84(1):54-9. doi: 10.3109/17453674.2013.765639. Epub 2013 Jan 23.

Abstract

BACKGROUND AND PURPOSE

There have been few prospective studies examining young and middle-aged patients with hip fracture. We therefore investigated background data, risk factors, and the trauma mechanism in young and middle-aged patients with femoral neck fracture.

PATIENTS AND METHODS

185 patients, 27 young (20-49 years old) and 158 middle-aged (50-69 years old) were prospectively included in a multicenter study lasting 3 years. Background data and risk factors for osteoporosis and fracture were obtained, and the type of injury was classified as low-energy trauma, high-energy trauma, or sports injury.

RESULTS

In the young age group, the fracture occurred because of low-energy trauma in two-fifths of patients and because of sport injury in two-fifths of patients. The rest occurred because of high-energy trauma. The corresponding proportions for the middle-aged group were four-fifths, one tenth, and one tenth (p < 0.001). There was a higher proportion of men (19/27) in the young group than in the middle-aged group (69/158) (p = 0.001). One fifth of the young patients were smokers as compared to two-fifths in the middle-age group (p = 0.04). One quarter of the patients reported high-volume alcohol drinking, with no difference between the two groups. Furthermore, three-quarters of the young patients and four-fifths of the middle-aged patients had one or more risk factors for osteoporosis and fracture.

INTERPRETATION

A minority of patients in each age group had high-energy trauma as the cause of their femoral neck fracture. Lifestyle factors and other non-trauma-related risk factors appear to have been important contributors to the occurrence of femoral neck fracture in both age groups.

摘要

背景与目的

鲜有前瞻性研究针对中青年髋部骨折患者进行探讨。因此,我们针对中青年股骨颈骨折患者的背景资料、危险因素和创伤机制进行了研究。

患者与方法

本研究为一项历时 3 年的多中心前瞻性研究,共纳入 185 例患者,其中 27 例患者年龄为 20-49 岁(年轻组),158 例患者年龄为 50-69 岁(中老年组)。收集患者的骨质疏松和骨折相关危险因素,并对损伤类型进行分类,包括低能量创伤、高能量创伤和运动损伤。

结果

在年轻组中,1/5 的患者因低能量创伤导致骨折,1/5 的患者因运动损伤导致骨折,其余 3/5 的患者因高能量创伤导致骨折;而在中老年组中,相应的比例分别为 4/5、1/10 和 1/10(p < 0.001)。年轻组中男性患者比例(19/27)高于中老年组(69/158)(p = 0.001)。年轻组中有 1/5 的患者吸烟,而中老年组中有 2/5 的患者吸烟(p = 0.04)。1/4 的患者报告饮酒量较大,但两组间无差异。此外,年轻组中 3/4 的患者和中老年组中 4/5 的患者存在 1 种或多种骨质疏松和骨折的危险因素。

结论

在每个年龄组中,均有少数患者因高能量创伤导致股骨颈骨折。生活方式因素和其他非创伤相关的危险因素似乎在两个年龄组中均对股骨颈骨折的发生起重要作用。

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Eur J Trauma Emerg Surg. 2009 Feb;35(1):40-2. doi: 10.1007/s00068-008-7177-y. Epub 2008 Jul 22.
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Osteoporos Int. 2005 Jul;16(7):737-42. doi: 10.1007/s00198-004-1734-y. Epub 2004 Sep 29.
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Smoking and fracture risk: a meta-analysis.吸烟与骨折风险:一项荟萃分析。
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