Putz Cornelia, Wiedenhöfer Bernd, Gerner Hans J, Hüttinger Karl, Fürstenberg Carl H
Orthopedic University Hospital Heidelberg, Heidelberg, Germany.
Orthopedic University Hospital Heidelberg, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany.
Eur J Trauma Emerg Surg. 2010 Apr;36(2):169-75. doi: 10.1007/s00068-009-8068-6. Epub 2009 Mar 2.
Bone graft harvesting from the iliac crest constitutes the gold standard in spinal surgery due to its osteogenic, osteoconductive and osteoinductive properties. Large amounts of autograft can provoke complications like donor site morbidity, pain and the need for a second operation. Therefore, research into bone graft substitutes is of great interest. Silicate-substituted calcium phosphate (Actifuse(TM) Synthetic Bone Graft, ApaTech Ltd, London) was used in combination with morselized corticocancellous graft in a transarticular stabilization (modified Magerl) of a completely tetraplegic patient with an unstable atlantoaxial fracture. Computed tomography showed bone bridging between the segment C1/C2, the surface of the implant and the remodeled bone at follow-up at 8 months. The use of silicate-substituted calcium phosphate as a bone graft extender in spinal surgery could be an alternative to autografting from the iliac crest. Vegetative symptoms are often underestimated but can be triggered by donor site morbidity or pain in patients after spinal cord injury.
由于具有成骨、骨传导和骨诱导特性,从髂嵴获取骨移植材料是脊柱手术的金标准。大量自体骨移植可能引发诸如供区并发症、疼痛以及需要二次手术等问题。因此,骨移植替代物的研究备受关注。在一名患有不稳定寰枢椎骨折的完全性四肢瘫痪患者的经关节稳定术(改良马格勒术式)中,硅酸钙磷酸盐(Actifuse™合成骨移植材料,ApaTech有限公司,伦敦)与碎皮质松质骨移植材料联合使用。计算机断层扫描显示,在8个月的随访中,C1/C2节段、植入物表面和重塑骨之间形成了骨桥接。在脊柱手术中使用硅酸钙磷酸盐作为骨移植扩展材料可能是髂嵴自体骨移植的一种替代方法。自主神经症状常常被低估,但可能由脊髓损伤患者的供区并发症或疼痛引发。