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[重症监护医学中的镇痛]

[Analgesia in intensive care medicine].

作者信息

Ortlepp J R, Luethje F, Walz R

机构信息

Klinik für Innere Medizin und Intensivmedizin, Asklepios Kliniken Schildautal, Karl-Herold-Str. 1, 38723, Seesen, Deutschland.

Internistische Intensivstation, Klinik für Innere Medizin und Intensivmedizin, Asklepios Kliniken Schildautal, Seesen, Deutschland.

出版信息

Med Klin Intensivmed Notfmed. 2016 Feb;111(1):6-13. doi: 10.1007/s00063-015-0127-7. Epub 2016 Jan 27.

DOI:10.1007/s00063-015-0127-7
PMID:26815840
Abstract

BACKGROUND

The administration of sedatives and analgesics on the intensive care unit (ICU) is routine daily practice. The correct discrimination between delirium, pain and anxiety or confusion is essential for the strategy and selection of medication. The correct pain therapy and sedation are essential for patient quality of life on the ICU and for the prognosis.

OBJECTIVE

The aim of this article is to present state of the art recommendations on the classification of pain and pain therapy on the ICU.

MATERIAL AND METHODS

An online search was carried out in PubMed for publications on the topics of "pain" and "ICU".

RESULTS

Critical care patients are frequently subjected to many procedures and situations which can cause pain. The perception of pain is, among other things, influenced by the degree of orientation, anxiety and the degree of sedation. The administration of analgesics and non-pharmacological approaches are effective in reducing the stress perceived by patients.

DISCUSSION

The main aim is improvement in the awareness of nursing and medical personnel for pain inducers and pain perception in ICU patients. The classification of pain must be made objectively. Therapeutic targets must be defined and in addition to the correct selection of pain medication, non-pharmacological approaches must also be consistently implemented.

摘要

背景

在重症监护病房(ICU)使用镇静剂和镇痛药是日常常规操作。正确区分谵妄、疼痛、焦虑或意识模糊对于用药策略和药物选择至关重要。正确的疼痛治疗和镇静对于ICU患者的生活质量和预后至关重要。

目的

本文旨在介绍关于ICU疼痛分类和疼痛治疗的最新建议。

材料与方法

在PubMed上进行在线搜索,查找有关“疼痛”和“ICU”主题的出版物。

结果

重症监护患者经常会经历许多可能导致疼痛的操作和情况。疼痛的感知除其他因素外,还受定向程度、焦虑和镇静程度的影响。使用镇痛药和非药物方法可有效减轻患者感受到的压力。

讨论

主要目标是提高护理人员和医务人员对ICU患者疼痛诱发因素和疼痛感知的认识。必须客观地进行疼痛分类。必须确定治疗目标,除了正确选择止痛药物外,还必须始终如一地实施非药物方法。

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1
[Analgesia in intensive care medicine].[重症监护医学中的镇痛]
Med Klin Intensivmed Notfmed. 2016 Feb;111(1):6-13. doi: 10.1007/s00063-015-0127-7. Epub 2016 Jan 27.
2
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本文引用的文献

1
The Impact of High Versus Low Sedation Dosing Strategy on Cognitive Dysfunction in Survivors of Intensive Care Units: A Systematic Review and Meta-Analysis.高剂量与低剂量镇静策略对重症监护病房幸存者认知功能障碍的影响:一项系统评价和荟萃分析。
J Cardiovasc Thorac Res. 2015;7(2):43-8. doi: 10.15171/jcvtr.2015.10.
2
Mutual relationship between anxiety and pain in the intensive care unit and its effect on medications.重症监护病房中焦虑与疼痛的相互关系及其对药物治疗的影响。
J Crit Care. 2015 Oct;30(5):1043-8. doi: 10.1016/j.jcrc.2015.05.025. Epub 2015 Jun 3.
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Analysis of Complaints from Patients During Mechanical Ventilation After Cardiac Surgery: A Retrospective Study.
J Cardiothorac Vasc Anesth. 2015 Aug;29(4):990-4. doi: 10.1053/j.jvca.2015.01.036. Epub 2015 Jan 29.
4
Emotional disorders in pairs of patients and their family members during and after ICU stay.重症监护病房(ICU)住院期间及出院后患者及其家庭成员的情绪障碍
PLoS One. 2015 Jan 23;10(1):e0115332. doi: 10.1371/journal.pone.0115332. eCollection 2015.
5
The use of the bispectral index in the detection of pain in mechanically ventilated adults in the intensive care unit: a review of the literature.双谱指数在重症监护病房机械通气成人疼痛检测中的应用:文献综述
Pain Res Manag. 2015 Jan-Feb;20(1):e33-7. doi: 10.1155/2015/981419. Epub 2014 Jul 22.
6
Early sedation and clinical outcomes of mechanically ventilated patients: a prospective multicenter cohort study.机械通气患者的早期镇静与临床结局:一项前瞻性多中心队列研究
Crit Care. 2014 Jul 21;18(4):R156. doi: 10.1186/cc13995.
7
Daily sedation interruption versus no daily sedation interruption for critically ill adult patients requiring invasive mechanical ventilation.对于需要有创机械通气的成年重症患者,每日中断镇静与不中断镇静的比较。
Cochrane Database Syst Rev. 2014 Jul 9;2014(7):CD009176. doi: 10.1002/14651858.CD009176.pub2.
8
Long-term outcome of delirium during intensive care unit stay in survivors of critical illness: a prospective cohort study.危重症幸存者在重症监护病房住院期间谵妄的长期结局:一项前瞻性队列研究。
Crit Care. 2014 Jun 18;18(3):R125. doi: 10.1186/cc13929.
9
Enteral naloxone for the treatment of opioid-induced constipation in the medical intensive care unit.肠内纳洛酮用于治疗医学重症监护病房中的阿片类药物引起的便秘。
J Crit Care. 2014 Oct;29(5):803-7. doi: 10.1016/j.jcrc.2014.04.005. Epub 2014 Apr 18.
10
Propofol is associated with favorable outcomes compared with benzodiazepines in ventilated intensive care unit patients.丙泊酚与苯二氮䓬类药物相比,与通气重症监护病房患者的良好结局相关。
Am J Respir Crit Care Med. 2014 Jun 1;189(11):1383-94. doi: 10.1164/rccm.201312-2291OC.