成年患者急性未分化发热性疾病的病因——来自印度北部一家三级护理医院的经验
Aetiologies of Acute Undifferentiated Febrile illness in Adult Patients - an Experience from a Tertiary Care Hospital in Northern India.
作者信息
Mittal Garima, Ahmad Sohaib, Agarwal R K, Dhar Minakshi, Mittal Manish, Sharma Shiwani
机构信息
Assistant Professor, Department of Microbiology, Himalayan Institute of Medical Sciences, SRH University , Jolly Grant, Dehradun, Uttarakhand, India .
Associate Professor, Department of Medicine, Himalayan Institute of Medical Sciences, SRH University , Jolly Grant, Dehradun, Uttarakhand, India .
出版信息
J Clin Diagn Res. 2015 Dec;9(12):DC22-4. doi: 10.7860/JCDR/2015/11168.6990. Epub 2015 Dec 1.
INTRODUCTION
Acute undifferentiated febrile illness (AUFI) is a common clinical entity in most of the hospitals. The fever can be potentially fatal if the aetiology is not recognized and appropriately treated early.
AIM
To describe the aetiology of fever among patients in a tertiary care hospital in Northern India.
MATERIALS AND METHODS
A one-year retro-prospective, observational study was conducted in adults (age>18years) presenting with undifferentiated febrile illness (of duration 5-14 days). Diagnosis was confirmed by suitable laboratory tests after exhaustive clinical examination.
RESULTS
A total of 2547 patients with AUFI were evaluated. Of these, 1663 (65.3%) were males and 884 (34.7%) were females. Dengue (37.54%); enteric fever (16.5%); scrub typhus (14.42%); bacterial sepsis (10.3%); malaria (6.8%); hepatitis A (1.9%); hepatitis E (1.4%); leptospirosis (0.14%); were the main infections while no specific diagnosis could be delineated in 11%. Mixed infections were noted in 48 (1.9%) patients.
CONCLUSION
A good clinical acumen supported by the basic investigations can help diagnose the cause of fever with reasonable certainty.
引言
急性未分化发热性疾病（AUFI）在大多数医院都是常见的临床病症。如果病因未被识别且早期未得到适当治疗，发热可能会致命。
目的
描述印度北部一家三级护理医院患者发热的病因。
材料与方法
对出现未分化发热性疾病（病程5 - 14天）的成年人（年龄>18岁）进行了为期一年的回顾性前瞻性观察研究。在进行详尽的临床检查后，通过适当的实验室检查确诊。
结果
共评估了2547例AUFI患者。其中，男性1663例（65.3%），女性884例（34.7%）。登革热（37.54%）；伤寒（16.5%）；恙虫病（14.42%）；细菌性败血症（10.3%）；疟疾（6.8%）；甲型肝炎（1.9%）；戊型肝炎（1.4%）；钩端螺旋体病（0.14%）是主要感染病因，而11%的患者无法明确具体诊断。48例（1.9%）患者存在混合感染。
结论
基础检查支持下的良好临床敏锐度有助于较为准确地诊断发热原因。
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