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印度北阿坎德邦一家三级医疗保健机构中季风季节急性发热疾病流行的病因模式研究。

A Study of Etiological Pattern in an Epidemic of Acute Febrile Illness during Monsoon in a Tertiary Health Care Institute of Uttarakhand, India.

作者信息

Singh Ragini, Singh S P, Ahmad Niaz

机构信息

Associate Professor, Department of Pediatrics, SGRR Institute of Medical & Health Sciences , Patel Nagar, Dehradun, Uttarakhand, India .

Professor, Department of Medicine, SGRR Institute of Medical & Health Sciences , Patel Nagar, Dehradun, Uttarakhand, India .

出版信息

J Clin Diagn Res. 2014 Jun;8(6):MC01-3. doi: 10.7860/JCDR/2014/8965.4435. Epub 2014 Jun 20.

Abstract

BACKGROUND

Many parts of India are endemic for the dengue, malaria, typhoid and scrub typhus infections. The relative contribution of these illnesses in an outbreak of acute febrile illness is not known in this region.

OBJECTIVE

The present study was conducted to find out the etiological pattern in an epidemic of acute febrile illness in Uttarakhand during the monsoon period. The study also focuses on concurrent infections and tries to find out the mortality outcomes.

MATERIALS AND METHODS

A retrospective study of four months was conducted on 1141 patients who presented with fever, and were suspected to have dengue, malaria, typhoid or scrub typhus. Patients of 12-years of age or above were included in the study. Serological tests for dengue, malaria, typhoid and scrub typhus were performed. Slides for malaria parasite were examined. In case of enteric fever only culture positive cases were included in the study.

RESULT

Among the 1141 febrile patients dengue was detected in 812(71.2 %), malaria in 146(12.8%), typhoid in 92(8.1%) and scrub typhus in 69(6.0%) cases. Mixed infection was noted in 22(1.9%).

CONCLUSION

Maximum (71.2 %) cases of fever were caused by dengue but significant number (32.3%) of patients suffered from malaria typhoid and scrub typhus. Many (1.9%) suffered from concurrent and multiple infections.

摘要

背景

印度许多地区是登革热、疟疾、伤寒和恙虫病感染的流行区。在该地区,这些疾病在急性发热性疾病暴发中所起的相对作用尚不清楚。

目的

本研究旨在查明季风期北阿坎德邦急性发热性疾病流行的病因模式。该研究还关注合并感染情况,并试图找出死亡率结果。

材料与方法

对1141例出现发热且疑似患有登革热、疟疾、伤寒或恙虫病的患者进行了为期四个月的回顾性研究。12岁及以上的患者纳入研究。进行了登革热、疟疾、伤寒和恙虫病的血清学检测。检查了疟原虫玻片。对于伤寒,仅将培养阳性的病例纳入研究。

结果

在1141例发热患者中,检测出登革热812例(71.2%),疟疾146例(12.8%),伤寒92例(8.1%),恙虫病69例(6.0%)。发现22例(1.9%)为混合感染。

结论

发热病例中最多(71.2%)由登革热引起,但相当数量(32.3%)的患者患有疟疾、伤寒和恙虫病。许多患者(1.9%)患有合并感染和多重感染。

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