Reynolds P M, Byrne M J
Aust N Z J Med. 1977 Apr;7(2):169-71. doi: 10.1111/j.1445-5994.1977.tb04688.x.
In three patients with metastatic carcinoma of the breast, control of a malignant pericardial effusion was achieved with a single pericardiocentesis followed by intensive systemic combination chemotherapy. No patient required reaspiration or any other form of local treatment. A trial of this conservative initial approach is therefore recommended in patients with pericardial effusions due to breast carcinoma. Its use in those with other tumours likely to be sensitive to systemic chemotherapy warrants further evaluation.
在3例转移性乳腺癌患者中，通过单次心包穿刺抽液并随后进行强化全身联合化疗，实现了对恶性心包积液的控制。没有患者需要再次抽液或任何其他形式的局部治疗。因此，对于因乳腺癌导致心包积液的患者，建议尝试这种保守的初始治疗方法。在那些可能对全身化疗敏感的其他肿瘤患者中使用这种方法，值得进一步评估。
